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putative hydroxyacid dehydrogenase [ Saccharomyces cerevisiae S288C ]

Gene ID: 852690, updated on 2-Nov-2024

Summary

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Official Full Name
putative hydroxyacid dehydrogenase
Primary source
SGD:S000003153
Locus tag
YGL185C
See related
AllianceGenome:SGD:S000003153; FungiDB:YGL185C; VEuPathDB:YGL185C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Located in cytoplasm. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (153167..154306, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene cytochrome c oxidase subunit IV Neighboring gene Tpn1p Neighboring gene cystathionine beta-lyase STR3 Neighboring gene Mnd1p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The ORF YNL274c (GOR1) codes for glyoxylate reductase in Saccharomyces cerevisiae. Rintala E, et al. Yeast, 2007 Feb. PMID 17173333
  2. Ser3p (Yer081wp) and Ser33p (Yil074cp) are phosphoglycerate dehydrogenases in Saccharomyces cerevisiae. Albers E, et al. J Biol Chem, 2003 Mar 21. PMID 12525494
  3. Stereoselective, biocatalytic reductions of alpha-chloro-beta-keto esters. Kaluzna IA, et al. J Org Chem, 2005 Jan 7. PMID 15624945
  4. Genome-wide protein interaction screens reveal functional networks involving Sm-like proteins. Fromont-Racine M, et al. Yeast, 2000 Jun 30. PMID 10900456, Free PMC Article
  5. The nucleotide sequence of Saccharomyces cerevisiae chromosome VII. Tettelin H, et al. Nature, 1997 May 29. PMID 9169869

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables NAD binding IEA
Inferred from Electronic Annotation
more info
  
enables glyoxylate reductase (NADPH) activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables hydroxypyruvate reductase [NAD(P)H] activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables phosphoglycerate dehydrogenase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
putative hydroxyacid dehydrogenase
NP_011330.1
  • Putative protein with sequence similar to hydroxyacid dehydrogenases; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    153167..154306 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181050.1 → NP_011330.1  TPA: putative hydroxyacid dehydrogenase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011330.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VTW9, P53100
    UniProtKB/TrEMBL
    A6ZU03, B3LHN4, B5VIE6, C7GX09, C8Z867, N1PA04
    Conserved Domains (1) summary
    cd12168
    Location:10 → 367
    Mand_dh_like; D-Mandelate Dehydrogenase-like dehydrogenases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53100.1

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