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GPG1 Gpg1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852756, updated on 2-Nov-2024

Summary

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Official Symbol
GPG1
Official Full Name
Gpg1p
Primary source
SGD:S000003089
Locus tag
YGL121C
See related
AllianceGenome:SGD:S000003089; FungiDB:YGL121C; VEuPathDB:YGL121C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in invasive growth in response to glucose limitation. Acts upstream of or within negative regulation of amyloid fibril formation. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See GPG1 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (280777..281157, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene ribosomal 40S subunit protein S2 Neighboring gene mRNA-binding protein NAB2 Neighboring gene DEAH-box ATP-dependent RNA helicase PRP43 Neighboring gene protein kinase COQ8

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A G-protein gamma subunit mimic is a general antagonist of prion propagation in Saccharomyces cerevisiae. Ishiwata M, et al. Proc Natl Acad Sci U S A, 2009 Jan 20. PMID 19129493, Free PMC Article
  2. Transcriptional profiling of Saccharomyces cerevisiae cells under adhesion-inducing conditions. Kleinschmidt M, et al. Mol Genet Genomics, 2005 Jun. PMID 15843968
  3. Disruption of six novel Saccharomyces cerevisiae genes reveals that YGL129c is necessary for growth in non-fermentable carbon sources, YGL128c for growth at low or high temperatures and YGL125w is implicated in the biosynthesis of methionine. Tizón B, et al. Yeast, 1999 Jan 30. PMID 10029993
  4. The Galpha protein Gpa2 controls yeast differentiation by interacting with kelch repeat proteins that mimic Gbeta subunits. Harashima T, et al. Mol Cell, 2002 Jul. PMID 12150916
  5. Heterologous gln/asn-rich proteins impede the propagation of yeast prions by altering chaperone availability. Yang Z, et al. PLoS Genet, 2013. PMID 23358669, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in invasive growth in response to glucose limitation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within negative regulation of amyloid fibril formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Gpg1p
NP_011394.1
  • Proposed gamma subunit of the heterotrimeric G protein; interacts with the receptor Gpr1p; involved in regulation of pseudohyphal growth; requires Gpb1p or Gpb2p to interact with Gpa2p; overproduction causes prion curing

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    280777..281157 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180986.1 → NP_011394.1  TPA: Gpg1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011394.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VU27, P53130
    UniProtKB/TrEMBL
    A6ZU61, B3LHI1, C7GM14, C8Z8D0, G2WDY1, N1P3G7
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53130.1

Gene LinkOut

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