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YBP2 Ybp2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852820, updated on 28-Oct-2024

Summary

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Official Symbol
YBP2
Official Full Name
Ybp2p
Primary source
SGD:S000003028
Locus tag
YGL060W
See related
AllianceGenome:SGD:S000003028; FungiDB:YGL060W; VEuPathDB:YGL060W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
YBH1
Summary
Involved in mitotic spindle organization. Located in kinetochore. [provided by Alliance of Genome Resources, Oct 2024]
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Genomic context

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See YBP2 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (390065..391990)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene pyruvate carboxylase 1 Neighboring gene Duo1p Neighboring gene protein kinase PKP2 Neighboring gene E2 ubiquitin-conjugating protein RAD6

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. YBP1 and its homologue YBP2/YBH1 influence oxidative-stress tolerance by nonidentical mechanisms in Saccharomyces cerevisiae. Gulshan K, et al. Eukaryot Cell, 2004 Apr. PMID 15075262, Free PMC Article
  2. Suppressors of ipl1-2 in components of a Glc7 phosphatase complex, Cdc48 AAA ATPase, TORC1, and the kinetochore. Robinson LC, et al. G3 (Bethesda), 2012 Dec. PMID 23275890, Free PMC Article
  3. Ybp2 associates with the central kinetochore of Saccharomyces cerevisiae and mediates proper mitotic progression. Ohkuni K, et al. PLoS One, 2008 Feb 20. PMID 18286174, Free PMC Article
  4. A network of proteins around Rvs167p and Rvs161p, two proteins related to the yeast actin cytoskeleton. Bon E, et al. Yeast, 2000 Sep 30. PMID 10992286
  5. Yeast screens identify the RNA polymerase II CTD and SPT5 as relevant targets of BRCA1 interaction. Bennett CB, et al. PLoS One, 2008 Jan 16. PMID 18197258, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in cellular response to oxidative stress IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cellular response to oxidative stress IEA
Inferred from Electronic Annotation
more info
  
involved_in mitotic spindle organization IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in kinetochore IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Ybp2p
NP_011455.1
  • Central kinetochore associated protein; mediates mitotic progression; interacts with several central kinetochore proteins and centromeric histone Cse4p; role in resistance to oxidative stress; similar to Slk19p; YBP2 has a paralog, YBP1, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    390065..391990
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180925.1 → NP_011455.1  TPA: Ybp2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011455.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VU81, P53169
    UniProtKB/TrEMBL
    B3LHC9, C7GRJ6
    Conserved Domains (1) summary
    pfam08568
    Location:1 → 633
    Kinetochor_Ybp2; Uncharacterized protein family, YAP/Alf4/glomulin
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53169.1

Gene LinkOut

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