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SDS23 Sds23p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852824, updated on 2-Nov-2024

Summary

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Official Symbol
SDS23
Official Full Name
Sds23p
Primary source
SGD:S000003024
Locus tag
YGL056C
See related
AllianceGenome:SGD:S000003024; FungiDB:YGL056C; VEuPathDB:YGL056C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable protein serine/threonine phosphatase inhibitor activity. Involved in septum digestion after cytokinesis. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See SDS23 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (396035..397618, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene E2 ubiquitin-conjugating protein RAD6 Neighboring gene Gep7p Neighboring gene stearoyl-CoA 9-desaturase Neighboring gene cornichon family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional conservation between fission yeast moc1/sds23 and its two orthologs, budding yeast SDS23 and SDS24, and phenotypic differences in their disruptants. Goldar MM, et al. Biosci Biotechnol Biochem, 2005 Jul. PMID 16041152
  2. Identification of novel genes to assign enhanced tolerance to osmotic stress in Saccharomyces cerevisiae. Kim B, et al. FEMS Microbiol Lett, 2018 Jul 1. PMID 29931330
  3. Identification of phosphatase 2A-like Sit4-mediated signalling and ubiquitin-dependent protein sorting as modulators of caffeine sensitivity in S. cerevisiae. Hood-DeGrenier JK. Yeast, 2011 Mar. PMID 21360731
  4. SAC3 may link nuclear protein export to cell cycle progression. Jones AL, et al. Proc Natl Acad Sci U S A, 2000 Mar 28. PMID 10716708, Free PMC Article
  5. Physiological effects of unassembled chaperonin Cct subunits in the yeast Saccharomyces cerevisiae. Kabir MA, et al. Yeast, 2005 Feb. PMID 15704212

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables protein serine/threonine phosphatase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cellular response to glucose starvation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cellular response to glucose starvation IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of mitotic metaphase/anaphase transition IEA
Inferred from Electronic Annotation
more info
  
involved_in septum digestion after cytokinesis IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus HDA PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Sds23p
NP_011459.2
  • Protein involved in cell separation during budding; one of two S. cerevisiae homologs (Sds23p and Sds24p) of the S. pombe Sds23 protein, which is implicated in APC/cyclosome regulation; SDS23 has a paralog, SDS24, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    396035..397618 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180921.2 → NP_011459.2  TPA: Sds23p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011459.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VU85, P53172, Q6B1R7
    UniProtKB/TrEMBL
    G2WE41, N1P9R5
    Conserved Domains (2) summary
    smart00116
    Location:276 → 322
    CBS; Domain in cystathionine beta-synthase and other proteins
    cd02205
    Location:190 → 259
    CBS_pair_SF; CBS repeat [structural motif]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53172.2

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