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PRM8 pheromone-regulated DUP240 family protein PRM8 [ Saccharomyces cerevisiae S288C ]

Gene ID: 852828, updated on 2-Nov-2024

Summary

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Official Symbol
PRM8
Official Full Name
pheromone-regulated DUP240 family protein PRM8
Primary source
SGD:S000003021
Locus tag
YGL053W
See related
AllianceGenome:SGD:S000003021; FungiDB:YGL053W; VEuPathDB:YGL053W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to be involved in vesicle-mediated transport. Located in endoplasmic reticulum and plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See PRM8 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (402589..403302)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene cornichon family protein Neighboring gene tRNA-Glu Neighboring gene DUP240 family protein MST27 Neighboring gene tRNA-Arg

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The characterization of two new clusters of duplicated genes suggests a 'Lego' organization of the yeast Saccharomyces cerevisiae chromosomes. Feuermann M, et al. Yeast, 1997 Jul. PMID 9234674
  2. Expansion and contraction of the DUP240 multigene family in Saccharomyces cerevisiae populations. Leh-Louis V, et al. Genetics, 2004 Aug. PMID 15342502, Free PMC Article
  3. Suppression of coatomer mutants by a new protein family with COPI and COPII binding motifs in Saccharomyces cerevisiae. Sandmann T, et al. Mol Biol Cell, 2003 Aug. PMID 12925749, Free PMC Article
  4. Multiple cargo binding sites on the COPII subunit Sec24p ensure capture of diverse membrane proteins into transport vesicles. Miller EA, et al. Cell, 2003 Aug 22. PMID 12941277
  5. Prm1p, a pheromone-regulated multispanning membrane protein, facilitates plasma membrane fusion during yeast mating. Heiman MG, et al. J Cell Biol, 2000 Oct 30. PMID 11062271, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum IMP
Inferred from Mutant Phenotype
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane ISM
Inferred from Sequence Model
more info
 PubMed 
located_in plasma membrane IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

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Preferred Names
pheromone-regulated DUP240 family protein PRM8
NP_011462.1
  • Pheromone-regulated protein; contains with 2 predicted transmembrane segments and an FF sequence, a motif involved in COPII binding; forms a complex with Prp9p in the ER; member of DUP240 gene family; PRM8 has a paralog, PRM9, that arose from a segmental duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    402589..403302
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180918.1 → NP_011462.1  TPA: pheromone-regulated DUP240 family protein PRM8 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011462.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VU88, P53174
    UniProtKB/TrEMBL
    Q687B0
    Conserved Domains (1) summary
    pfam00674
    Location:80 → 171
    DUP; DUP family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53174.1

Gene LinkOut

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