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AGA2 Aga2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852851, updated on 2-Nov-2024

Summary

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Official Symbol
AGA2
Official Full Name
Aga2p
Primary source
SGD:S000003000
Locus tag
YGL032C
See related
AllianceGenome:SGD:S000003000; FungiDB:YGL032C; VEuPathDB:YGL032C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables cell adhesion molecule binding activity. Involved in agglutination involved in conjugation with cellular fusion. Located in fungal-type cell wall. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See AGA2 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (436570..436833, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Hop2p Neighboring gene ribosomal 60S subunit protein L24A Neighboring gene ribosomal 60S subunit protein L30

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Saccharomyces cerevisiae a- and alpha-agglutinin: characterization of their molecular interaction. Cappellaro C, et al. EMBO J, 1991 Dec. PMID 1756718, Free PMC Article
  2. Purification and characterization of the inducible a agglutinin of Saccharomyces cerevisiae. Watzele M, et al. EMBO J, 1988 May. PMID 3044782, Free PMC Article
  3. [Cell surface display of Yarrowia lipolytica lipase Lip2 in Saccharomyces cerevisiae with a-agglutinin as carrier protein]. Liu W, et al. Wei Sheng Wu Xue Bao, 2008 Nov. PMID 19149173
  4. NY-ESO-1 protein glycosylated by yeast induces enhanced immune responses. Wadle A, et al. Yeast, 2010 Nov. PMID 20672253
  5. Construction of an in vitro trans-sialylation system: surface display of Corynebacterium diphtheriae sialidase on Saccharomyces cerevisiae. Kim S, et al. Appl Microbiol Biotechnol, 2010 Oct. PMID 20711574

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables cell adhesion molecule binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in agglutination involved in conjugation with cellular fusion IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in agglutination involved in conjugation with cellular fusion IEA
Inferred from Electronic Annotation
more info
  
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum HDA PubMed 
located_in fungal-type cell wall IDA
Inferred from Direct Assay
more info
 PubMed 
located_in fungal-type cell wall IEA
Inferred from Electronic Annotation
more info
  
located_in fungal-type vacuole HDA PubMed 

General protein information

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Preferred Names
Aga2p
NP_011483.3
  • Adhesion subunit of a-agglutinin of a-cells; C-terminal sequence acts as a ligand for alpha-agglutinin (Sag1p) during agglutination, modified with O-linked oligomannosyl chains, linked to anchorage subunit Aga1p via two disulfide bonds

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    436570..436833 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180897.3 → NP_011483.3  TPA: Aga2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011483.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VUA6, P32781
    UniProtKB/TrEMBL
    A6ZUW2, B3LIP4, C7GT49, C8Z8L0, G2WE62, N1P3P2
    Conserved Domains (1) summary
    pfam17366
    Location:27 → 87
    AGA2; A-agglutinin-binding subunit Aga2
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P32781.1

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