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RPL24A ribosomal 60S subunit protein L24A [ Saccharomyces cerevisiae S288C ]

Gene ID: 852852, updated on 28-Oct-2024

Summary

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Official Symbol
RPL24A
Official Full Name
ribosomal 60S subunit protein L24A
Primary source
SGD:S000002999
Locus tag
YGL031C
See related
AllianceGenome:SGD:S000002999; FungiDB:YGL031C; VEuPathDB:YGL031C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
RPL30A
Summary
Enables RNA binding activity. Involved in translational elongation and translational initiation. Part of cytosolic large ribosomal subunit. Orthologous to human RPL24 (ribosomal protein L24). [provided by Alliance of Genome Resources, Oct 2024]
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Genomic context

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See RPL24A in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (437467..437934, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene Hop2p Neighboring gene Aga2p Neighboring gene ribosomal 60S subunit protein L30 Neighboring gene Cgr1p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A yeast ribosomal protein gene whose intron is in the 5' leader. Mitra G, et al. J Biol Chem, 1984 Jul 25. PMID 6086628
  2. Ribosomal protein L30 is dispensable in the yeast Saccharomyces cerevisiae. Baronas-Lowell DM, et al. Mol Cell Biol, 1990 Oct. PMID 2204809, Free PMC Article
  3. Ribosomal protein eL24, involved in two intersubunit bridges, stimulates translation initiation and elongation. Kisly I, et al. Nucleic Acids Res, 2019 Jan 10. PMID 30407570, Free PMC Article
  4. Yeast ribosomal protein L24 affects the kinetics of protein synthesis and ribosomal protein L39 improves translational accuracy, while mutants lacking both remain viable. Dresios J, et al. Biochemistry, 2000 Jun 20. PMID 10852723
  5. Compensatory mutations in the L30e kink-turn RNA-protein complex. Schweppe JJ, et al. Biochim Biophys Acta, 2009 Jun-Aug. PMID 19460470, Free PMC Article

See all (127) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables RNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translational elongation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in translational initiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ribosomal 60S subunit protein L24A
NP_011484.1
  • Ribosomal 60S subunit protein L24A; forms two bridges within ribosome, stimulates translation initiation and elongation; homologous to mammalian ribosomal protein L24, no bacterial homolog; RPL24A has a paralog, RPL24B, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    437467..437934 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180896.1 → NP_011484.1  TPA: ribosomal 60S subunit protein L24A [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011484.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A2TBN7, D6VUA7, P04449
    UniProtKB/TrEMBL
    A6ZUG0, A6ZUW3, B3LIP3, C8Z8L1, G2WE63, N1P5K0
    Conserved Domains (1) summary
    pfam01246
    Location:2 → 64
    Ribosomal_L24e; Ribosomal protein L24e
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P04449.1

Gene LinkOut

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