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DPC29 Dpc29p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852904, updated on 17-May-2024

Summary

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Gene symbol
DPC29
Gene description
Dpc29p
Primary source
FungiDB:YGR021W
Locus tag
YGR021W
See related
SGD:S000003253; AllianceGenome:SGD:S000003253; VEuPathDB:YGR021W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Located in mitochondrion. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Orthologous to human TACO1 (translational activator of cytochrome c oxidase I). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See DPC29 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (527632..528504)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene 4-aminobutyrate transaminase Neighboring gene H(+)-transporting V1 sector ATPase subunit F Neighboring gene Mtl1p Neighboring gene tRNA-Asp

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. DPC29 promotes post-initiation mitochondrial translation in Saccharomyces cerevisiae. Hubble KA, et al. Nucleic Acids Res, 2023 Feb 22. PMID 36620885, Free PMC Article
  2. Suppressors of a cold-sensitive mutation in yeast U4 RNA define five domains in the splicing factor Prp8 that influence spliceosome activation. Kuhn AN, et al. Genetics, 2000 Aug. PMID 10924465, Free PMC Article
  3. Definition of a High-Confidence Mitochondrial Proteome at Quantitative Scale. Morgenstern M, et al. Cell Rep, 2017 Jun 27. PMID 28658629, Free PMC Article
  4. Molecular Connectivity of Mitochondrial Gene Expression and OXPHOS Biogenesis. Singh AP, et al. Mol Cell, 2020 Sep 17. PMID 32877643
  5. Elucidation of the interaction proteome of mitochondrial chaperone Hsp78 highlights its role in protein aggregation during heat stress. Jaworek W, et al. J Biol Chem, 2022 Oct. PMID 36115461, Free PMC Article

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. DPC29 promotes post-initiation mitochondrial translation in Saccharomyces cerevisiae.
    Title: DPC29 promotes post-initiation mitochondrial translation in Saccharomyces cerevisiae.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within mitochondrial translation IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within mitochondrial translation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in matrix side of mitochondrial inner membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Dpc29p
NP_011535.1
  • General post-initiation mitochondrial translation factor; peripherally associated with the matrix side of the mitochondrial inner membrane; interacts with mitoribosomal proteins in actively translating cells; human ortholog TACO1 complements the yeast null mutant

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    527632..528504
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181150.1 → NP_011535.1  TPA: Dpc29p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011535.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VUF6, P53212
    UniProtKB/TrEMBL
    A0A7I9BWE0, A6ZV11, B3LIJ7, B5VIY1, C7GK89, C8Z8R5, G2WEB2, N1P225
    Conserved Domains (1) summary
    COG0217
    Location:26 → 289
    TACO1; Transcriptional and/or translational regulatory protein YebC/TACO1 [Transcription, Translation, ribosomal structure and biogenesis]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53212.1

Gene LinkOut

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