U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

RME1 Rme1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852935, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
RME1
Official Full Name
Rme1p
Primary source
SGD:S000003276
Locus tag
YGR044C
See related
AllianceGenome:SGD:S000003276; FungiDB:YGR044C; VEuPathDB:YGR044C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
CSP1
Summary
Enables DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including G1/S transition of mitotic cell cycle; positive regulation of invasive growth in response to glucose limitation; and regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See RME1 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (582990..583892, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene Mte1p Neighboring gene sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate transaldolase NQM1 Neighboring gene uncharacterized protein Neighboring gene putative phosphatidate cytidylyltransferase

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Regulation of mating and meiosis in yeast by the mating-type region. Kassir Y, et al. Genetics, 1976 Feb. PMID 770230, Free PMC Article
  2. Intercalation of a new tier of transcription regulation into an ancient circuit. Booth LN, et al. Nature, 2010 Dec 16. PMID 21164485, Free PMC Article
  3. Repression and activation domains of RME1p structurally overlap, but differ in genetic requirements. Blumental-Perry A, et al. Mol Biol Cell, 2002 May. PMID 12006664, Free PMC Article
  4. Rme1, which controls CLN2 expression in Saccharomyces cerevisiae, is a nuclear protein that is cell cycle regulated. Frenz LM, et al. Mol Genet Genomics, 2001 Nov. PMID 11713667
  5. A C-terminal segment with properties of alpha-helix is essential for DNA binding and in vivo function of zinc finger protein Rme1p. Shimizu M, et al. J Biol Chem, 2001 Oct 5. PMID 11466318

See all (64) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
Process Evidence Code Pubs
involved_in G1/S transition of mitotic cell cycle IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in cell division IEA
Inferred from Electronic Annotation
more info
  
involved_in meiotic cell cycle IEA
Inferred from Electronic Annotation
more info
  
involved_in meiotic cell cycle IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of meiotic nuclear division IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of invasive growth in response to glucose limitation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in nucleus HDA PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Rme1p
NP_011558.1
  • Zinc finger protein involved in control of meiosis; prevents meiosis by repressing IME1 expression and promotes mitosis by activating CLN2 expression; directly repressed by a1-alpha2 regulator; mediates cell type control of sporulation; relocalizes from nucleus to cytoplasm upon DNA replication stress

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    582990..583892 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181173.1 → NP_011558.1  TPA: Rme1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011558.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VUI2, P32338, Q45TA6
    UniProtKB/TrEMBL
    A6ZV32, B3LIH7, B5VIZ7, B8XW44, C7GXN0, C8Z8U0, G2WED4, Q45T98, Q45TA4
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P32338.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools