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RPL11B ribosomal 60S subunit protein L11B [ Saccharomyces cerevisiae S288C ]

Gene ID: 852976, updated on 28-Oct-2024

Summary

Official Symbol
RPL11B
Official Full Name
ribosomal 60S subunit protein L11B
Primary source
SGD:S000003317
Locus tag
YGR085C
See related
AllianceGenome:SGD:S000003317; FungiDB:YGR085C; VEuPathDB:YGR085C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Involved in ribosomal large subunit assembly. Part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 7 and T-cell acute lymphoblastic leukemia. Orthologous to human RPL11 (ribosomal protein L11). [provided by Alliance of Genome Resources, Oct 2024]
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Genomic context

See RPL11B in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (648383..648907, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene translation initiation factor eIF2B subunit delta Neighboring gene mitochondrial 37S ribosomal protein YmS-A Neighboring gene lipid-binding protein PIL1 Neighboring gene ncRNA

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables rRNA binding IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
 
enables structural constituent of ribosome IC
Inferred by Curator
more info
PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cytoplasmic translation IC
Inferred by Curator
more info
PubMed 
involved_in ribosomal large subunit assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in translation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 
located_in ribosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ribosomal 60S subunit protein L11B
NP_011599.1
  • Ribosomal 60S subunit protein L11B; expressed at half the level of Rpl11Ap; involved in ribosomal assembly; depletion causes degradation of 60S proteins and RNA; homologous to mammalian ribosomal protein L11 and bacterial L5; RPL11B has a paralog, RPL11A, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    648383..648907 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181214.1NP_011599.1  TPA: ribosomal 60S subunit protein L11B [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011599.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VUL7, Q3E757
    UniProtKB/TrEMBL
    A6ZV67, B3LIE1, B5VJ29, C8Z8X9, G2WEG9, N1P3L3
    Conserved Domains (1) summary
    PTZ00156
    Location:2172
    PTZ00156; 60S ribosomal protein L11; Provisional