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YGR122W uncharacterized protein [ Saccharomyces cerevisiae S288C ]

Gene ID: 853020, updated on 17-May-2024

Summary

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Gene symbol
YGR122W
Gene description
uncharacterized protein
Primary source
FungiDB:YGR122W
Locus tag
YGR122W
See related
SGD:S000003354; AllianceGenome:SGD:S000003354; VEuPathDB:YGR122W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in negative regulation of transcription by RNA polymerase II and nuclear-transcribed mRNA catabolic process, non-stop decay. Located in cytoplasm; nucleus; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See YGR122W in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (733935..735143)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene ammonium permease MEP1 Neighboring gene uncharacterized protein Neighboring gene tRNA-Arg Neighboring gene protein serine/threonine phosphatase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. PalC, one of two Bro1 domain proteins in the fungal pH signalling pathway, localizes to cortical structures and binds Vps32. Galindo A, et al. Traffic, 2007 Oct. PMID 17696968, Free PMC Article
  2. Relationship of DFG16 to the Rim101p pH response pathway in Saccharomyces cerevisiae and Candida albicans. Barwell KJ, et al. Eukaryot Cell, 2005 May. PMID 15879523, Free PMC Article
  3. Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method. Xie MW, et al. Proc Natl Acad Sci U S A, 2005 May 17. PMID 15883373, Free PMC Article
  4. Interaction maps of the Saccharomyces cerevisiae ESCRT-III protein Snf7. Sciskala B, et al. Eukaryot Cell, 2013 Nov. PMID 24058170, Free PMC Article
  5. Protein interaction verification and functional annotation by integrated analysis of genome-scale data. Kemmeren P, et al. Mol Cell, 2002 May. PMID 12049748

See all (51) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in nuclear-transcribed mRNA catabolic process, non-stop decay IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in nucleus HDA PubMed 
located_in plasma membrane HDA PubMed 

General protein information

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Preferred Names
uncharacterized protein
NP_011637.3
  • Protein that may be involved in pH regulation; probable ortholog of A. nidulans PalC, which is involved in pH regulation and binds to the ESCRT-III complex; null mutant does not properly process Rim101p and has decreased resistance to rapamycin; GFP-fusion protein is cytoplasmic; relative distribution to cytoplasm increases upon DNA replication stress

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    733935..735143
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181251.3 → NP_011637.3  TPA: uncharacterized protein YGR122W [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011637.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VUQ4, P53272
    UniProtKB/TrEMBL
    A0A8H4C0J7, A6ZUD6, B3LIA6, C7GSX3, C8Z914, N1P419
    Conserved Domains (1) summary
    pfam17306
    Location:80 → 402
    DUF5355; Family of unknown function (DUF5355)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53272.1

Gene LinkOut

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