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VPS62 Vps62p [ Saccharomyces cerevisiae S288C ]

Gene ID: 853042, updated on 18-Sep-2024

Summary

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Official Symbol
VPS62
Official Full Name
Vps62p
Primary source
SGD:S000003373
Locus tag
YGR141W
See related
AllianceGenome:SGD:S000003373; FungiDB:YGR141W; VEuPathDB:YGR141W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in protein targeting to vacuole. Located in endoplasmic reticulum and fungal-type vacuole membrane. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See VPS62 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (770569..771972)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene spermine transporter Neighboring gene Cbf2p Neighboring gene Btn2p Neighboring gene tRNA-Ala

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Prevacuolar compartment morphology in vps mutants of Saccharomyces cerevisiae. Hedman JM, et al. Cell Biol Int, 2007 Oct. PMID 17543551
  2. Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae. Bonangelino CJ, et al. Mol Biol Cell, 2002 Jul. PMID 12134085, Free PMC Article
  3. The yeast vacuolar membrane proteome. Wiederhold E, et al. Mol Cell Proteomics, 2009 Feb. PMID 19001347
  4. Identifying Interaction Partners of Yeast Protein Disulfide Isomerases Using a Small Thiol-Reactive Cross-Linker: Implications for Secretory Pathway Proteostasis. Freije BJ, et al. Chem Res Toxicol, 2022 Feb 21. PMID 35084835, Free PMC Article
  5. Global analysis of SUMO chain function reveals multiple roles in chromatin regulation. Srikumar T, et al. J Cell Biol, 2013 Apr 1. PMID 23547032, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in protein targeting to vacuole HMP PubMed 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum HDA PubMed 
located_in fungal-type vacuole membrane HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Vps62p
NP_011657.1
  • Vacuolar protein sorting (VPS) protein; required for cytoplasm to vacuole targeting of proteins; targeted to vacuole via AP-3 pathway; VPS62 has a paralog, TDA6, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    770569..771972
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181270.1 → NP_011657.1  TPA: Vps62p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011657.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VUS1, P53285
    UniProtKB/TrEMBL
    A6ZUF3, B3LI89, B5VJ84, C7GXU2, C8Z934
    Conserved Domains (1) summary
    pfam06101
    Location:202 → 297
    Vps62; Vacuolar protein sorting-associated protein 62
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53285.1

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