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CBP4 Cbp4p [ Saccharomyces cerevisiae S288C ]

Gene ID: 853085, updated on 2-Nov-2024

Summary

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Official Symbol
CBP4
Official Full Name
Cbp4p
Primary source
SGD:S000003406
Locus tag
YGR174C
See related
AllianceGenome:SGD:S000003406; FungiDB:YGR174C; VEuPathDB:YGR174C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in mitochondrial respiratory chain complex III assembly. Located in mitochondrial membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See CBP4 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (845893..846405, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene Rbg2p Neighboring gene tRNA-Gly Neighboring gene uncharacterized protein Neighboring gene squalene monooxygenase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of CBP4, a new gene essential for the expression of ubiquinol-cytochrome c reductase in Saccharomyces cerevisiae. Crivellone MD. J Biol Chem, 1994 Aug 19. PMID 8063753
  2. A structural model of the cytochrome C reductase/oxidase supercomplex from yeast mitochondria. Heinemeyer J, et al. J Biol Chem, 2007 Apr 20. PMID 17322303
  3. Organization of assembly factors Cbp3p and Cbp4p and their effect on bc(1) complex assembly in Saccharomyces cerevisiae. Kronekova Z, et al. Curr Genet, 2005 Apr. PMID 15759116
  4. Cbp3-Cbp6 interacts with the yeast mitochondrial ribosomal tunnel exit and promotes cytochrome b synthesis and assembly. Gruschke S, et al. J Cell Biol, 2011 Jun 13. PMID 21670217, Free PMC Article
  5. Timing of dimerization of the bc(1) complex during mitochondrial respiratory chain assembly. Stephan K, et al. Biochim Biophys Acta Bioenerg, 2020 Jun 1. PMID 32119834

See all (49) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Cbp3p and Cbp4p are two mitochondrial proteins which are postulated to act as chaperones in bc(1) complex formation.
    Title: Organization of assembly factors Cbp3p and Cbp4p and their effect on bc(1) complex assembly in Saccharomyces cerevisiae.
  2. model of the cytochrome C reductase/oxidase supercomplex from Saccharomyces mitochondria
    Title: A structural model of the cytochrome C reductase/oxidase supercomplex from yeast mitochondria.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in mitochondrial respiratory chain complex III assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial respiratory chain complex III assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrial membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrial membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Cbp4p
NP_011690.3
  • Mitochondrial protein required for assembly of cytochrome bc1 complex; interacts with the Cbp3p-Cbp6p complex and newly synthesized cytochrome b (Cobp) to promote assembly of Cobp into the cytochrome bc1 complex

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    845893..846405 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181303.3 → NP_011690.3  TPA: Cbp4p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011690.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    G2WEQ5, N1P608
    Conserved Domains (1) summary
    pfam07960
    Location:28 → 151
    CBP4
Nucleotide Protein
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