U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

YCH1 phosphatase YCH1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 853117, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
YCH1
Official Full Name
phosphatase YCH1
Primary source
SGD:S000003435
Locus tag
YGR203W
See related
AllianceGenome:SGD:S000003435; FungiDB:YGR203W; VEuPathDB:YGR203W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables phosphatase activity and thiosulfate sulfurtransferase activity. Involved in dephosphorylation. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See YCH1 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (905237..905683)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene choline-phosphate cytidylyltransferase Neighboring gene trifunctional formate-tetrahydrofolate ligase/methenyltetrahydrofolate cyclohydrolase/methylenetetrahydrofolate dehydrogenase ADE3 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Crystallization and preliminary X-ray diffraction analysis of Saccharomyces cerevisiae Ygr203p, a homologue of Acr2 arsenate reductase. Moon J, et al. Acta Crystallogr D Biol Crystallogr, 2000 Jun. PMID 10818363
  2. Crystal structure of Saccharomyces cerevisiae Ygr203w, a homolog of single-domain rhodanese and Cdc25 phosphatase catalytic domain. Yeo HK, et al. Proteins, 2009 Aug 1. PMID 19382206
  3. Protein tyrosine phosphatases: mechanisms of catalysis and regulation. Denu JM, et al. Curr Opin Chem Biol, 1998 Oct. PMID 9818190
  4. A small CDC25 dual-specificity tyrosine-phosphatase isoform in Arabidopsis thaliana. Landrieu I, et al. Proc Natl Acad Sci U S A, 2004 Sep 7. PMID 15329414, Free PMC Article
  5. A model of Cdc25 phosphatase catalytic domain and Cdk-interaction surface based on the presence of a rhodanese homology domain. Hofmann K, et al. J Mol Biol, 1998 Sep 11. PMID 9733650

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Crystal structure of Saccharomyces cerevisiae Ygr203w, a homolog of single-domain rhodanese and Cdc25 phosphatase catalytic domain.
    Title: Crystal structure of Saccharomyces cerevisiae Ygr203w, a homolog of single-domain rhodanese and Cdc25 phosphatase catalytic domain.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables phosphoprotein phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein tyrosine phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables thiosulfate sulfurtransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in dephosphorylation IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
phosphatase YCH1
NP_011719.1
  • Phosphatase with sequence similarity to Mih1p; member of the Cdc25p subfamily of tyrosine phosphatases and Arr2p, an arsenate reductase, based on the presence of a rhodanese-homology domain; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    905237..905683
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181332.1 → NP_011719.1  TPA: phosphatase YCH1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011719.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VUY5, P42937
    UniProtKB/TrEMBL
    A6ZUL3, B3LI34, C8Z995, G2WET1, N1P4A0
    Conserved Domains (1) summary
    cd01531
    Location:9 → 132
    Acr2p; Eukaryotic arsenate resistance proteins are members of the Rhodanese Homology Domain superfamily. Included in this CD is the Saccharomyces cerevisiae arsenate reductase protein, Acr2p, and other yeast and plant homologs.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P42937.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools