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RTA1 Rta1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 853127, updated on 18-Sep-2024

Summary

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Official Symbol
RTA1
Official Full Name
Rta1p
Primary source
SGD:S000003445
Locus tag
YGR213C
See related
AllianceGenome:SGD:S000003445; FungiDB:YGR213C; VEuPathDB:YGR213C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See RTA1 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (918512..919465, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene zinc finger-containing protein ZPR1 Neighboring gene N-acetyltransferase Neighboring gene ribosomal 40S subunit protein S0A Neighboring gene mitochondrial 37S ribosomal protein RSM27

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The regulatory inputs controlling pleiotropic drug resistance and hypoxic response in yeast converge at the promoter of the aminocholesterol resistance gene RTA1. Kołaczkowska A, et al. FEMS Yeast Res, 2012 May. PMID 22129104
  2. Characterization of the Saccharomyces cerevisiae RTA1 gene involved in 7-aminocholesterol resistance. Soustre I, et al. Curr Genet, 1996 Jul 31. PMID 8660468
  3. Loop 5 region is important for the activity of the long-chain base transporter Rsb1. Makuta H, et al. J Biochem, 2017 Feb 1. PMID 28175317
  4. Role of PUG1 in inducible porphyrin and heme transport in Saccharomyces cerevisiae. Protchenko O, et al. Eukaryot Cell, 2008 May. PMID 18326586, Free PMC Article
  5. The nucleotide sequence of Saccharomyces cerevisiae chromosome VII. Tettelin H, et al. Nature, 1997 May 29. PMID 9169869

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. RTA1 promoter responds to the status of the major repressors of hypoxic genes and activators of pleiotropic drug resistance.
    Title: The regulatory inputs controlling pleiotropic drug resistance and hypoxic response in yeast converge at the promoter of the aminocholesterol resistance gene RTA1.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Rta1p
NP_011729.1
  • Protein involved in 7-aminocholesterol resistance; has seven potential membrane-spanning regions; expression is induced under both low-heme and low-oxygen conditions; member of the fungal lipid-translocating exporter (LTE) family of protein; RTA1 has a paralog, YLR046C, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    918512..919465 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181342.1 → NP_011729.1  TPA: Rta1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011729.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VUZ6, E9P922, P53047
    UniProtKB/TrEMBL
    A6ZUM4, N1P642
    Conserved Domains (1) summary
    pfam04479
    Location:72 → 275
    RTA1; RTA1 like protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53047.1

Gene LinkOut

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