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RTT102 Rtt102p [ Saccharomyces cerevisiae S288C ]

Gene ID: 853192, updated on 29-Jun-2024

Summary

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Gene symbol
RTT102
Gene description
Rtt102p
Primary source
FungiDB:YGR275W
Locus tag
YGR275W
See related
SGD:S000003507; AllianceGenome:SGD:S000003507; VEuPathDB:YGR275W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in chromosome segregation; nucleosome disassembly; and transcription elongation from RNA polymerase II promoter. Located in nucleus. Part of RSC-type complex and SWI/SNF complex. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See RTT102 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (1043276..1043749)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene histone acetyltransferase Neighboring gene Rnh70p Neighboring gene putative pantetheine-phosphate adenylyltransferase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structural insights into assembly and function of the RSC chromatin remodeling complex. Baker RW, et al. Nat Struct Mol Biol, 2021 Jan. PMID 33288924, Free PMC Article
  2. Actin-related proteins regulate the RSC chromatin remodeler by weakening intramolecular interactions of the Sth1 ATPase. Turegun B, et al. Commun Biol, 2018. PMID 29809203, Free PMC Article
  3. Subunit Rtt102 controls the conformation of the Arp7/9 heterodimer and its interactions with nucleotide and the catalytic subunit of SWI/SNF remodelers. Turegun B, et al. J Biol Chem, 2013 Dec 13. PMID 24189066, Free PMC Article
  4. Structure of an actin-related subcomplex of the SWI/SNF chromatin remodeler. Schubert HL, et al. Proc Natl Acad Sci U S A, 2013 Feb 26. PMID 23401505, Free PMC Article
  5. Proteomic analysis of chromatin-modifying complexes in Saccharomyces cerevisiae identifies novel subunits. Lee KK, et al. Biochem Soc Trans, 2004 Dec. PMID 15506919

See all (80) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. a function for subunit Rtt102 as a stabilizing factor for the Arp7/9 heterodime
    Title: Subunit Rtt102 controls the conformation of the Arp7/9 heterodimer and its interactions with nucleotide and the catalytic subunit of SWI/SNF remodelers.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables DNA translocase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in chromatin remodeling IC
Inferred by Curator
more info
 PubMed 
involved_in chromatin remodeling IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in chromatin remodeling IEA
Inferred from Electronic Annotation
more info
  
involved_in chromosome segregation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in nucleosome disassembly IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in transcription elongation by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
part_of RSC-type complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of RSC-type complex IEA
Inferred from Electronic Annotation
more info
  
part_of SWI/SNF complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of SWI/SNF complex IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus HDA PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Rtt102p
NP_011791.4
  • Component of both the SWI/SNF and RSC chromatin remodeling complexes; suggested role in chromosome maintenance; possible weak regulator of Ty1 transposition; protein abundance increases in response to DNA replication stress

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    1043276..1043749
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181404.3 → NP_011791.4  TPA: Rtt102p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011791.4

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VV52, P53330
    UniProtKB/TrEMBL
    A0A8H8UL05, A6ZUT1, C7GNG0, C8Z9G8, G2WEZ8
    Conserved Domains (1) summary
    pfam09510
    Location:5 → 140
    Rtt102p; Rtt102p-like transcription regulator protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53330.2

Gene LinkOut

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