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CBP1 Cbp1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 853221, updated on 2-Nov-2024

Summary

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Official Symbol
CBP1
Official Full Name
Cbp1p
Primary source
SGD:S000003745
Locus tag
YJL209W
See related
AllianceGenome:SGD:S000003745; FungiDB:YJL209W; VEuPathDB:YJL209W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables mRNA binding activity. Involved in aerobic respiration and mitochondrial mRNA catabolic process. Located in mitochondrion. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See CBP1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
1
Sequence:
Chromosome: X; NC_001142.9 (38005..39969)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene oligopeptide transporter OPT1 Neighboring gene ubiquitin-protein ligase peroxin 2 Neighboring gene ribonuclease Neighboring gene Laa1p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001142.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Yeast CBP1 mRNA 3' end formation is regulated during the induction of mitochondrial function. Mayer SA, et al. Mol Cell Biol, 1991 Feb. PMID 1990285, Free PMC Article
  2. Identification of the CBP1 polypeptide in mitochondrial extracts from Saccharomyces cerevisiae. Weber ER, et al. J Biol Chem, 1990 Jan 25. PMID 2104848
  3. CBP1 function is required for stability of a hybrid cob-oli1 transcript in yeast mitochondria. Mittelmeier TM, et al. Curr Genet, 1990 Dec. PMID 2150347
  4. The yeast CBP1 gene produces two differentially regulated transcripts by alternative 3'-end formation. Mayer SA, et al. Mol Cell Biol, 1989 Oct. PMID 2573826, Free PMC Article
  5. Assembly of the mitochondrial membrane system. Nucleotide sequence of a yeast nuclear gene (CBP1) involved in 5' end processing of cytochrome b pre-mRNA. Dieckmann CL, et al. J Biol Chem, 1984 Apr 25. PMID 6325407

See all (45) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Mitochondrial localization of the splicing endonuclease complex is required for the cleavage of the CBP1 mRNA.
    Title: The tRNA Splicing Endonuclease Complex Cleaves the Mitochondria-localized CBP1 mRNA.
  2. Data suggests that Cbp1 is loosely associated with the mitochondrial membrane through weak hydrophobic interactions and it is part of a single 900,000-Da complex. .
    Title: The mitochondrial message-specific mRNA protectors Cbp1 and Pet309 are associated in a high-molecular weight complex.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables mRNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in aerobic respiration IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in mitochondrial mRNA catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion HDA PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Cbp1p
NP_012326.1
  • Mitochondrial protein, regulator of COB mRNA stability and translation; interacts with the 5'-untranslated region of the COB mRNA; found in a complex at the inner membrane along with Pet309p; localizes to mitochondrial foci upon DNA replication stress

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    38005..39969
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181642.1 → NP_012326.1  TPA: Cbp1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012326.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VVY5, P07252
    UniProtKB/TrEMBL
    N1P174
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P07252.1

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