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MRPL8 mitochondrial 54S ribosomal protein YmL8 [ Saccharomyces cerevisiae S288C ]

Gene ID: 853382, updated on 9-Jun-2024

Summary

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Gene symbol
MRPL8
Gene description
mitochondrial 54S ribosomal protein YmL8
Primary source
FungiDB:YJL063C
Locus tag
YJL063C
See related
SGD:S000003599; AllianceGenome:SGD:S000003599; VEuPathDB:YJL063C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
bL17m; HRD238
Summary
A structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in mitochondrion. Part of mitochondrial large ribosomal subunit. Orthologous to human MRPL17 (mitochondrial ribosomal protein L17). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See MRPL8 in Genome Data Viewer
Location:
chromosome: X
Exon count:
1
Sequence:
Chromosome: X; NC_001142.9 (315759..316475, complement)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene Mpm1p Neighboring gene Dls1p Neighboring gene Coa3p Neighboring gene mannose-ethanolamine phosphotransferase LAS21

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001142.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mitochondrial transport of mitoribosomal proteins, YmL8 and YmL20, in Saccharomyces cerevisiae. Matsushita Y, et al. Eur J Biochem, 1993 Jun 1. PMID 8513807
  2. Cloning and characterization of nuclear genes for two mitochondrial ribosomal proteins in Saccharomyces cerevisiae. Kitakawa M, et al. Nucleic Acids Res, 1990 Mar 25. PMID 2183197, Free PMC Article
  3. DPC29 promotes post-initiation mitochondrial translation in Saccharomyces cerevisiae. Hubble KA, et al. Nucleic Acids Res, 2023 Feb 22. PMID 36620885, Free PMC Article
  4. Structure of the yeast mitochondrial large ribosomal subunit. Amunts A, et al. Science, 2014 Mar 28. PMID 24675956, Free PMC Article
  5. Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components. Gan X, et al. Eur J Biochem, 2002 Nov. PMID 12392552

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in mitochondrial translation IC
Inferred by Curator
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of mitochondrial large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
mitochondrial 54S ribosomal protein YmL8
NP_012472.1
  • Mitochondrial ribosomal protein of the large subunit

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    315759..316475 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181496.1 → NP_012472.1  TPA: mitochondrial 54S ribosomal protein YmL8 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012472.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VWB8, P22353
    UniProtKB/TrEMBL
    A0A8H4BYH9, A6ZPQ8, B3LQ46, B5VLB3, C7GR48, C8ZBF0, G2WGV2, N1P1A5
    Conserved Domains (2) summary
    TIGR00059
    Location:7 → 127
    L17; ribosomal protein L17
    pfam18502
    Location:129 → 238
    Mrpl_C; 54S ribosomal protein L8 C-terminal domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P22353.4

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