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KKQ8 putative serine/threonine protein kinase KKQ8 [ Saccharomyces cerevisiae S288C ]

Gene ID: 853686, updated on 18-Sep-2024

Summary

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Official Symbol
KKQ8
Official Full Name
putative serine/threonine protein kinase KKQ8
Primary source
SGD:S000001651
Locus tag
YKL168C
See related
AllianceGenome:SGD:S000001651; FungiDB:YKL168C; VEuPathDB:YKL168C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in cellular cation homeostasis; intracellular signal transduction; and protein phosphorylation. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See KKQ8 in Genome Data Viewer
Location:
chromosome: XI
Exon count:
1
Sequence:
Chromosome: XI; NC_001143.9 (131288..133462, complement)

Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene protein kinase NNK1 Neighboring gene mitochondrial 54S ribosomal protein YmL38/YmL34 Neighboring gene mitochondrial 54S ribosomal protein MRP49 Neighboring gene cAMP-dependent protein kinase catalytic subunit TPK3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001143.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Systematic screening of protein modifications in four kinases using affinity enrichment and mass spectrometry analysis with unrestrictive sequence alignment. Zhang K, et al. Anal Chim Acta, 2011 Apr 8. PMID 21458632
  2. Saccharomyces cerevisiae gene YMR291W/TDA1 mediates the in vivo phosphorylation of hexokinase isoenzyme 2 at serine-15. Kettner K, et al. FEBS Lett, 2012 Feb 17. PMID 22289182
  3. Detailed search for protein kinase(s) involved in plasma membrane H+-ATPase activity regulation of yeast cells. Pereira RR, et al. FEMS Yeast Res, 2015 Mar. PMID 25769530
  4. Substrate specificity analysis of protein kinase complex Dbf2-Mob1 by peptide library and proteome array screening. Mah AS, et al. BMC Biochem, 2005 Oct 21. PMID 16242037, Free PMC Article
  5. Snx4-assisted vacuolar targeting of transcription factors defines a new autophagy pathway for controlling ATG expression. Hanley SE, et al. Autophagy, 2021 Nov. PMID 33678121, Free PMC Article

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables histone H2AS1 kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in chromatin remodeling IEA
Inferred from Electronic Annotation
more info
  
involved_in intracellular monoatomic cation homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in phosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
putative serine/threonine protein kinase KKQ8
NP_012753.2
  • Putative serine/threonine protein kinase with unknown cellular role; KKQ8 has a paralog, HAL5, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001143.9 Reference assembly

    Range
    131288..133462 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179734.1 → NP_012753.2  TPA: putative serine/threonine protein kinase KKQ8 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012753.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A6ZZF6, D6VX31, P36004
    Conserved Domains (1) summary
    cl21453
    Location:418 → 712
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P36004.2

Gene LinkOut

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