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MCR1 cytochrome-b5 reductase [ Saccharomyces cerevisiae S288C ]

Gene ID: 853707, updated on 28-Oct-2024

Summary

Official Symbol
MCR1
Official Full Name
cytochrome-b5 reductase
Primary source
SGD:S000001633
Locus tag
YKL150W
See related
AllianceGenome:SGD:S000001633; FungiDB:YKL150W; VEuPathDB:YKL150W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables cytochrome-b5 reductase activity, acting on NAD(P)H. Involved in cellular response to oxidative stress and ergosterol biosynthetic process. Located in mitochondrial intermembrane space and mitochondrial outer membrane. [provided by Alliance of Genome Resources, Oct 2024]
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Genomic context

See MCR1 in Genome Data Viewer
Location:
chromosome: XI
Exon count:
1
Sequence:
Chromosome: XI; NC_001143.9 (166544..167452)

Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene phosphoglycerate mutase GPM1 Neighboring gene NADHX dehydratase Neighboring gene RNA lariat debranching enzyme Neighboring gene succinate dehydrogenase flavoprotein subunit SDH1

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
cytochrome-b5 reductase
NP_012772.1
  • Mitochondrial NADH-cytochrome b5 reductase; involved in ergosterol biosynthesis

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001143.9 Reference assembly

    Range
    166544..167452
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179716.1NP_012772.1  TPA: cytochrome-b5 reductase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012772.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A2TBM9, A6ZZH2, D6VX47, P36060
    UniProtKB/TrEMBL
    B3LQV1, B5VM14, C7GSN4, C8ZC25, G2WHN9, N1P2Y2
    Conserved Domains (1) summary
    cd06183
    Location:56302
    cyt_b5_reduct_like; Cytochrome b5 reductase catalyzes the reduction of 2 molecules of cytochrome b5 using NADH as an electron donor. Like ferredoxin reductases, these proteins have an N-terminal FAD binding subdomain and a C-terminal NADH binding subdomain, separated by a ...