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CWP2 Cwp2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 853765, updated on 3-Nov-2024

Summary

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Official Symbol
CWP2
Official Full Name
Cwp2p
Primary source
SGD:S000001956
Locus tag
YKL096W-A
See related
AllianceGenome:SGD:S000001956; FungiDB:YKL096W-A; VEuPathDB:YKL096W-A
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
LPR1; YKL097W-A
Summary
A structural constituent of cell wall. Involved in fungal-type cell wall organization. Located in fungal-type cell wall. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See CWP2 in Genome Data Viewer
Location:
chromosome: XI
Exon count:
1
Sequence:
Chromosome: XI; NC_001143.9 (259253..259531)

Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Cwp1p Neighboring gene mRNA splicing protein YJU2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001143.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. DNA sequence analysis of a 17 kb fragment of yeast chromosome XI physically localizes the MRB1 gene and reveals eight new open reading frames, including a homologue of the KIN1/KIN2 and SNF1 protein kinases. Pallier C, et al. Yeast, 1993 Oct. PMID 8256524
  2. Dominant suppressor mutation bypasses the sphingolipid requirement for growth of Saccharomyces cells at low pH: role of the CWP2 gene. Skrzypek M, et al. Curr Genet, 2000 Nov. PMID 11126778
  3. Suppressor gene analysis reveals an essential role for sphingolipids in transport of glycosylphosphatidylinositol-anchored proteins in Saccharomyces cerevisiae. Skrzypek M, et al. J Bacteriol, 1997 Mar. PMID 9045807, Free PMC Article
  4. Improved cellulase production in recombinant Saccharomyces cerevisiae by disrupting the cell wall protein-encoding gene CWP2. Li J, et al. J Biosci Bioeng, 2020 Feb. PMID 31537451
  5. The retention mechanism of cell wall proteins in Saccharomyces cerevisiae. Wall-bound Cwp2p is beta-1,6-glucosylated. van der Vaart JM, et al. Biochim Biophys Acta, 1996 Dec 6. PMID 8980634

See all (63) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables structural constituent of cell wall IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of cell wall IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in fungal-type cell wall organization IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in fungal-type cell wall organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol HDA PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in fungal-type cell wall IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in side of membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Cwp2p
NP_012826.1
  • Covalently linked cell wall mannoprotein; major constituent of the cell wall; plays a role in stabilizing the cell wall; involved in low pH resistance; precursor is GPI-anchored

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001143.9 Reference assembly

    Range
    259253..259531
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180025.1 → NP_012826.1  TPA: Cwp2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012826.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VXJ1, P43497
    UniProtKB/TrEMBL
    A6ZZM0, B3LQZ7, B5VM61, C7GVL3, C8ZC78, G2WHT7, N1P7R2
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P43497.1

Gene LinkOut

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