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putative hydrolase [ Saccharomyces cerevisiae S288C ]

Gene ID: 853833, updated on 2-Nov-2024

Summary

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Official Full Name
putative hydrolase
Primary source
SGD:S000007242
Locus tag
YKL033W-A
See related
AllianceGenome:SGD:S000007242; FungiDB:YKL033W-A; VEuPathDB:YKL033W-A
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables 5'-nucleotidase activity and pseudouridine 5'-phosphatase activity. Orthologous to human PUDP (pseudouridine 5'-phosphatase). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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Location:
chromosome: XI
Exon count:
1
Sequence:
Chromosome: XI; NC_001143.9 (374505..375215)

Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene UTP glucose-1-phosphate uridylyltransferase Neighboring gene ubiquitin-protein ligase TUL1 Neighboring gene Tti1p Neighboring gene tRNA-Val

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001143.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Diversity of Haloacid Dehalogenase Superfamily Phosphatases from Saccharomyces cerevisiae: BIOCHEMICAL, STRUCTURAL, AND EVOLUTIONARY INSIGHTS. Kuznetsova E, et al. J Biol Chem, 2015 Jul 24. PMID 26071590, Free PMC Article
  2. Mass-murdering: deletion of twenty-three ORFs from Saccharomyces cerevisiae chromosome XI reveals five genes essential for growth and three genes conferring detectable mutant phenotype. Wysocki R, et al. Gene, 1999 Mar 18. PMID 10095102
  3. Enrichment-Based Proteogenomics Identifies Microproteins, Missing Proteins, and Novel smORFs in Saccharomyces cerevisiae. He C, et al. J Proteome Res, 2018 Jul 6. PMID 29897761
  4. A proteomic screen of Ty1 integrase partners identifies the protein kinase CK2 as a regulator of Ty1 retrotransposition. Barkova A, et al. Mob DNA, 2022 Nov 18. PMID 36401307, Free PMC Article
  5. Complete DNA sequence of yeast chromosome XI. Dujon B, et al. Nature, 1994 Jun 2. PMID 8196765

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables 5'-nucleotidase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables XMP 5'-nucleosidase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables pseudouridine 5'-phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables pseudouridine 5'-phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
putative hydrolase
NP_012891.4
  • hypothetical protein; similar to uncharacterized proteins from other fungi

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001143.9 Reference assembly

    Range
    374505..375215
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184335.3 → NP_012891.4  TPA: putative hydrolase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012891.4

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VXQ2, Q86ZR7
    UniProtKB/TrEMBL
    A6ZZT1, B3LR53, C7GP39, C8ZCD6, G2WHZ7, N1P2F6
    Conserved Domains (1) summary
    cd07529
    Location:7 → 202
    HAD_AtGPP-like; subfamily of beta-phosphoglucomutase-like family, similar to Arabidopsis thaliana Gpp1 and Gpp2
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q86ZR7.2

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