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SKA1 Ska1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 853845, updated on 18-Sep-2024

Summary

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Official Symbol
SKA1
Official Full Name
Ska1p
Primary source
SGD:S000001506
Locus tag
YKL023W
See related
AllianceGenome:SGD:S000001506; FungiDB:YKL023W; VEuPathDB:YKL023W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See SKA1 in Genome Data Viewer
Location:
chromosome: XI
Exon count:
1
Sequence:
Chromosome: XI; NC_001143.9 (393721..394554)

Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene bifunctional uridylate/adenylate kinase Neighboring gene Min9p Neighboring gene anaphase promoting complex subunit CDC16 Neighboring gene Mak11p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001143.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. From E-MAPs to module maps: dissecting quantitative genetic interactions using physical interactions. Ulitsky I, et al. Mol Syst Biol, 2008. PMID 18628749, Free PMC Article
  2. A specialised SKI complex assists the cytoplasmic RNA exosome in the absence of direct association with ribosomes. Zhang E, et al. EMBO J, 2019 Jul 15. PMID 31304628, Free PMC Article
  3. Cnm1 mediates nucleus-mitochondria contact site formation in response to phospholipid levels. Eisenberg-Bord M, et al. J Cell Biol, 2021 Nov 1. PMID 34694322, Free PMC Article
  4. Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast. Gupta R, et al. Mol Syst Biol, 2007. PMID 17551511, Free PMC Article
  5. Proteomics of yeast telomerase identified Cdc48-Npl4-Ufd1 and Ufd4 as regulators of Est1 and telomere length. Lin KW, et al. Nat Commun, 2015 Sep 14. PMID 26365526, Free PMC Article

See all (47) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in nuclear-transcribed mRNA catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Ska1p
NP_012902.4
  • SKI complex-associated protein; involved in 3'-5' degradation of long 3'UTR-containing mRNA, poorly translated mRNA, and other RNA regions devoid of ribosomes; proposed to assist the cytoplasmic exosome in a Ska1-SKI complex when a direct interaction between the ribosome and the SKI complex is absent

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001143.9 Reference assembly

    Range
    393721..394554
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179589.4 → NP_012902.4  TPA: Ska1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012902.4

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VXR2, P36103
    UniProtKB/TrEMBL
    A6ZZU1, C7GRI2, G2WI07, N1P2G8
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P36103.2

Gene LinkOut

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