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uncharacterized protein [ Saccharomyces cerevisiae S288C ]

Gene ID: 853888, updated on 18-Sep-2024

Summary

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Official Full Name
uncharacterized protein
Primary source
SGD:S000001726
Locus tag
YKR018C
See related
AllianceGenome:SGD:S000001726; FungiDB:YKR018C; VEuPathDB:YKR018C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Located in cytoplasm and nucleus. Orthologous to several human genes including TTC39B (tetratricopeptide repeat domain 39B). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: XI
Exon count:
1
Sequence:
Chromosome: XI; NC_001143.9 (473723..475900, complement)

Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene Mic60p Neighboring gene E3 ubiquitin-protein ligase HEL1 Neighboring gene Irs4p Neighboring gene Vps51p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001143.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A PhotoClick cholesterol-based quantitative proteomics screen for cytoplasmic sterol-binding proteins in Saccharomyces cerevisiae. Chauhan N, et al. Yeast, 2020 Jan. PMID 31758572
  2. Deletion of 24 open reading frames from chromosome XI from Saccharomyces cerevisiae and phenotypic analysis of the deletants. Zúñiga S, et al. Gene, 1999 Jun 11. PMID 10375630
  3. Membrane phospholipid alteration causes chronic ER stress through early degradation of homeostatic ER-resident proteins. Shyu P Jr, et al. Sci Rep, 2019 Jun 14. PMID 31201345, Free PMC Article
  4. Complete DNA sequence of yeast chromosome XI. Dujon B, et al. Nature, 1994 Jun 2. PMID 8196765
  5. Asymmetric Inheritance of Aggregated Proteins and Age Reset in Yeast Are Regulated by Vac17-Dependent Vacuolar Functions. Hill SM, et al. Cell Rep, 2016 Jul 19. PMID 27373154, Free PMC Article

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus HDA PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
NP_012943.1
  • hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; protein abundance increases in response to DNA replication stress; YKR018C has a paralog, IML2, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001143.9 Reference assembly

    Range
    473723..475900 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179808.1 → NP_012943.1  TPA: uncharacterized protein YKR018C [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012943.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VX83, P36114
    UniProtKB/TrEMBL
    C7GNP1, G2WI49, N1P0G5
    Conserved Domains (1) summary
    pfam10300
    Location:36 → 629
    DUF3808; Protein of unknown function (DUF3808)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P36114.1

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