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SKG1 Skg1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 853975, updated on 18-Sep-2024

Summary

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Official Symbol
SKG1
Official Full Name
Skg1p
Primary source
SGD:S000001808
Locus tag
YKR100C
See related
AllianceGenome:SGD:S000001808; FungiDB:YKR100C; VEuPathDB:YKR100C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
YKR099C-A
Summary
Involved in fungal-type cell wall organization. Located in cellular bud tip. Part of incipient cellular bud site. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See SKG1 in Genome Data Viewer
Location:
chromosome: XI
Exon count:
1
Sequence:
Chromosome: XI; NC_001143.9 (638901..639968, complement)

Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene ubiquitin-specific protease UBP11 Neighboring gene Bas1p Neighboring gene Sir1p Neighboring gene Flo10p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001143.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. SKG1, a suppressor gene of synthetic lethality of kex2Deltagas1Delta mutations, encodes a novel membrane protein that affects cell wall composition. Tomishige N, et al. Yeast, 2005 Jan 30. PMID 15645486
  2. A large-scale overexpression screen in Saccharomyces cerevisiae identifies previously uncharacterized cell cycle genes. Stevenson LF, et al. Proc Natl Acad Sci U S A, 2001 Mar 27. PMID 11274415, Free PMC Article
  3. Complete DNA sequence of yeast chromosome XI. Dujon B, et al. Nature, 1994 Jun 2. PMID 8196765
  4. A genetic interaction map centered on cohesin reveals auxiliary factors involved in sister chromatid cohesion in S. cerevisiae. Ming Sun S, et al. J Cell Sci, 2020 May 22. PMID 32299836, Free PMC Article
  5. A genome-wide enhancer screen implicates sphingolipid composition in vacuolar ATPase function in Saccharomyces cerevisiae. Finnigan GC, et al. Genetics, 2011 Mar. PMID 21196517, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. SKG1 encodes a novel protein that affects the cell wall polymer composition in the growing region of the cell.
    Title: SKG1, a suppressor gene of synthetic lethality of kex2Deltagas1Delta mutations, encodes a novel membrane protein that affects cell wall composition.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in cell wall organization IEA
Inferred from Electronic Annotation
more info
  
involved_in fungal-type cell wall organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cellular bud HDA PubMed 
located_in cellular bud membrane IEA
Inferred from Electronic Annotation
more info
  
located_in cellular bud tip IDA
Inferred from Direct Assay
more info
 PubMed 
located_in incipient cellular bud site IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Skg1p
NP_013026.2
  • Transmembrane protein with a role in cell wall polymer composition; localizes on inner surface of plasma membrane at bud and in daughter cell; SKG1 has a paralog, AIM20, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001143.9 Reference assembly

    Range
    638901..639968 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179890.1 → NP_013026.2  TPA: Skg1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013026.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A7A060, D6VXG1, P36169, Q86ZT0
    UniProtKB/TrEMBL
    N1P120
    Conserved Domains (1) summary
    pfam08693
    Location:2 → 34
    SKG6; Transmembrane alpha-helix domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P36169.2

Gene LinkOut

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