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AAD15 putative aryl-alcohol dehydrogenase [ Saccharomyces cerevisiae S288C ]

Gene ID: 853999, updated on 17-May-2024

Summary

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Gene symbol
AAD15
Gene description
putative aryl-alcohol dehydrogenase
Primary source
FungiDB:YOL165C
Locus tag
YOL165C
See related
SGD:S000005525; AllianceGenome:SGD:S000005525; VEuPathDB:YOL165C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable aryl-alcohol dehydrogenase (NADP+) activity. Predicted to be involved in cellular aldehyde metabolic process. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See AAD15 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (1647..2078, complement)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene sulfuric ester hydrolase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Deciphering the Origin, Evolution, and Physiological Function of the Subtelomeric Aryl-Alcohol Dehydrogenase Gene Family in the Yeast Saccharomyces cerevisiae. Yang DD, et al. Appl Environ Microbiol, 2018 Jan 1. PMID 29079624, Free PMC Article
  2. Analysis of the seven-member AAD gene set demonstrates that genetic redundancy in yeast may be more apparent than real. Delneri D, et al. Genetics, 1999 Dec. PMID 10581269, Free PMC Article
  3. Disruption of seven hypothetical aryl alcohol dehydrogenase genes from Saccharomyces cerevisiae and construction of a multiple knock-out strain. Delneri D, et al. Yeast, 1999 Nov. PMID 10572264
  4. The catabolism of amino acids to long chain and complex alcohols in Saccharomyces cerevisiae. Dickinson JR, et al. J Biol Chem, 2003 Mar 7. PMID 12499363
  5. Variation in gene duplicates with low synonymous divergence in Saccharomyces cerevisiae relative to Caenorhabditis elegans. Katju V, et al. Genome Biol, 2009. PMID 19594930, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables aryl-alcohol dehydrogenase (NADP+) activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cellular aldehyde metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
putative aryl-alcohol dehydrogenase
NP_014477.1
  • Putative aryl-alcohol dehydrogenase; similar to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role; AAD15 has a paralog, AAD3, that arose from a segmental duplication; members of the AAD gene family comprise three pairs (AAD3 + AAD15, AAD6/AAD16 + AAD4, AAD10 + AAD14) whose two genes are more related to one another than to other members of the family

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    1647..2078 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183418.1 → NP_014477.1  TPA: putative aryl-alcohol dehydrogenase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014477.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W1Q4, Q08361
    UniProtKB/TrEMBL
    A0A8H4BUN2, N1NY17
    Conserved Domains (1) summary
    cl00470
    Location:1 → 115
    AKR_SF; Aldo-keto reductase (AKR) superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q08361.1

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