IMA2 oligo-1,6-glucosidase IMA2 [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: IMA2
Official Full Name: oligo-1,6-glucosidase IMA2
Primary source: SGD:S000005517
Locus tag: YOL157C
See related: AllianceGenome:SGD:S000005517; FungiDB:YOL157C; VEuPathDB:YOL157C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Enables oligo-1,6-glucosidase activity and sucrose alpha-glucosidase activity. Involved in disaccharide catabolic process. Human ortholog(s) of this gene implicated in cystinuria. Orthologous to several human genes including SLC3A1 (solute carrier family 3 member 1). [provided by Alliance of Genome Resources, Apr 2022]
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Chromosome XV - NC_001147.6 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables alpha-1,4-glucosidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables alpha-amylase activity	IBA Inferred from Biological aspect of Ancestor more info
enables alpha-glucosidase activity	IEA Inferred from Electronic Annotation more info
enables glucan 1,4-alpha-maltotriohydrolase activity	IBA Inferred from Biological aspect of Ancestor more info
enables hydrolase activity, acting on glycosyl bonds	IEA Inferred from Electronic Annotation more info
enables oligo-1,6-glucosidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables oligo-1,6-glucosidase activity	IDA Inferred from Direct Assay more info	PubMed
enables oligo-1,6-glucosidase activity	IEA Inferred from Electronic Annotation more info
enables oligo-1,6-glucosidase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables sucrose alpha-glucosidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables sucrose alpha-glucosidase activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
involved_in disaccharide catabolic process	IEA Inferred from Electronic Annotation more info
involved_in disaccharide catabolic process	IGI Inferred from Genetic Interaction more info	PubMed
involved_in maltose catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in maltose metabolic process	IEA Inferred from Electronic Annotation more info
involved_in sucrose catabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

NP_014485.1

Isomaltase (alpha-1,6-glucosidase/alpha-methylglucosidase); preferred specificity for isomaltose, alpha-methylglucoside, and palatinose, but also exhibits alpha-1,2 glucosidase activity on sucrose and kojibiose, and can cleave the 1,3-alpha linkage of nigerose and turanose and the alpha-1,5 linkage of leucrose in vitro; not required for isomaltose utilization, but Ima2p overexpression allows the ima1 null mutant to grow on isomaltose

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The following sections contain reference sequences that belong to a specific genome build. Explain