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MSN1 Msn1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854033, updated on 2-Nov-2024

Summary

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Official Symbol
MSN1
Official Full Name
Msn1p
Primary source
SGD:S000005476
Locus tag
YOL116W
See related
AllianceGenome:SGD:S000005476; FungiDB:YOL116W; VEuPathDB:YOL116W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
FUP1; HRB382; MSS10; PHD2
Summary
Enables sequence-specific DNA binding activity. Involved in several processes, including cellular hyperosmotic salinity response; positive regulation of growth of unicellular organism as a thread of attached cells; and positive regulation of macromolecule metabolic process. Located in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See MSN1 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (99809..100957)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Rri2p Neighboring gene non-canonical poly(A) polymerase PAP2 Neighboring gene Pth4p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Increased dosage of a transcriptional activator gene enhances iron-limited growth of Saccharomyces cerevisiae. Eide D, et al. J Gen Microbiol, 1992 Feb. PMID 1564445
  2. Expression of yeast transcriptional activator MSN1 promotes accumulation of chromium and sulfur by enhancing sulfate transporter level in plants. Kim YJ, et al. FEBS Lett, 2006 Jan 9. PMID 16364322
  3. A multicopy suppressor gene, MSS10, restores STA2 expression in Saccharomyces cerevisiae strains containing the STA10 repressor gene. Lambrechts MG, et al. Curr Genet, 1996 May. PMID 8662191
  4. The putative transcriptional activator MSN1 promotes chromium accumulation in Saccharomyces cerevisiae. Chang KS, et al. Mol Cells, 2003 Dec 31. PMID 14744017
  5. Increased dosage of the MSN1 gene restores invertase expression in yeast mutants defective in the SNF1 protein kinase. Estruch F, et al. Nucleic Acids Res, 1990 Dec 11. PMID 2263457, Free PMC Article

See all (53) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular hyperosmotic salinity response IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in cellular hyperosmotic salinity response IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cellular response to heat IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cellular response to methylglyoxal IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of invasive growth in response to glucose limitation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of pseudohyphal growth IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of ribosomal protein gene transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of starch catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in nucleus HDA PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Msn1p
NP_014525.1
  • Transcriptional activator; involved in regulation of invertase and glucoamylase expression, invasive growth and pseudohyphal differentiation, iron uptake, chromium accumulation, and response to osmotic stress; localizes to the nucleus; relative distribution to the nucleus increases upon DNA replication stress

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    99809..100957
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183370.1 → NP_014525.1  TPA: Msn1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014525.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W1V1, P22148, Q12227, Q9URF6
    UniProtKB/TrEMBL
    B3LIU9, C7GSS0, G2WMC0, N1NXH5
    Conserved Domains (1) summary
    pfam12550
    Location:278 → 356
    GCR1_C; Transcriptional activator of glycolytic enzymes
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P22148.2

Gene LinkOut

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