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RRT8 Rrt8p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854109, updated on 2-Nov-2024

Summary

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Official Symbol
RRT8
Official Full Name
Rrt8p
Primary source
SGD:S000005408
Locus tag
YOL048C
See related
AllianceGenome:SGD:S000005408; FungiDB:YOL048C; VEuPathDB:YOL048C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in ascospore wall assembly. Located in ascospore wall and prospore membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See RRT8 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
2
Sequence:
Chromosome: XV; NC_001147.6 (240204..241310, complement)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Gal11p Neighboring gene glutathione synthase Neighboring gene Lds2p Neighboring gene serine/threonine protein kinase PSK2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A Conserved Machinery Underlies the Synthesis of a Chitosan Layer in the Candida Chlamydospore Cell Wall. Bemena LD, et al. mSphere, 2021 Apr 28. PMID 33910989, Free PMC Article
  2. In vitro reconstitution of the yeast spore wall dityrosine layer discloses the mechanism of its assembly. Bemena LD, et al. J Biol Chem, 2017 Sep 22. PMID 28794156, Free PMC Article
  3. Lipid droplet proteins, Lds1p, Lds2p, and Rrt8p, are implicated in membrane protein transport associated with ergosterol. Ueno K, et al. Biochem Biophys Res Commun, 2016 Jul 8. PMID 27216456
  4. Genetic identification of factors that modulate ribosomal DNA transcription in Saccharomyces cerevisiae. Hontz RD, et al. Genetics, 2009 May. PMID 19270272, Free PMC Article
  5. A highly redundant gene network controls assembly of the outer spore wall in S. cerevisiae. Lin CP, et al. PLoS Genet, 2013. PMID 23966878, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in ascospore wall assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in sporulation resulting in formation of a cellular spore IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in ascospore wall IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in ascospore wall IDA
Inferred from Direct Assay
more info
 PubMed 
located_in lipid droplet HDA PubMed 
is_active_in lipid droplet IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in lipid droplet IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in prospore membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in prospore membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in prospore membrane IEA
Inferred from Electronic Annotation
more info
  
located_in spore wall IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Rrt8p
NP_014594.2
  • Protein involved in spore wall assembly; shares similarity with Lds1p and Lds2p and a strain mutant for all 3 genes exhibits reduced dityrosine fluorescence relative to the single mutants; identified in a screen for mutants with increased levels of rDNA transcription; green fluorescent protein (GFP)-fusion protein localizes to lipid particles; protein abundance increases in response to DNA replication stress

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    240204..241310 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183302.1 → NP_014594.2  TPA: Rrt8p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014594.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W219, Q08219, Q870H5
    UniProtKB/TrEMBL
    B3LJ11, N1NWQ8
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q08219.2

Gene LinkOut

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