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LDS2 Lds2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854110, updated on 2-Nov-2024

Summary

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Official Symbol
LDS2
Official Full Name
Lds2p
Primary source
SGD:S000005407
Locus tag
YOL047C
See related
AllianceGenome:SGD:S000005407; FungiDB:YOL047C; VEuPathDB:YOL047C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in ascospore wall assembly. Located in ascospore wall; ascus lipid droplet; and prospore membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See LDS2 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
2
Sequence:
Chromosome: XV; NC_001147.6 (241614..242747, complement)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene glutathione synthase Neighboring gene Rrt8p Neighboring gene serine/threonine protein kinase PSK2 Neighboring gene Pex15p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. In vitro reconstitution of the yeast spore wall dityrosine layer discloses the mechanism of its assembly. Bemena LD, et al. J Biol Chem, 2017 Sep 22. PMID 28794156, Free PMC Article
  2. Lipid droplet proteins, Lds1p, Lds2p, and Rrt8p, are implicated in membrane protein transport associated with ergosterol. Ueno K, et al. Biochem Biophys Res Commun, 2016 Jul 8. PMID 27216456
  3. A highly redundant gene network controls assembly of the outer spore wall in S. cerevisiae. Lin CP, et al. PLoS Genet, 2013. PMID 23966878, Free PMC Article
  4. A visual screen of protein localization during sporulation identifies new components of prospore membrane-associated complexes in budding yeast. Lam C, et al. Eukaryot Cell, 2014 Mar. PMID 24390141, Free PMC Article
  5. Comprehensive and quantitative mapping of RNA-protein interactions across a transcribed eukaryotic genome. She R, et al. Proc Natl Acad Sci U S A, 2017 Apr 4. PMID 28325876, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in ascospore wall assembly IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in sporulation resulting in formation of a cellular spore IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in ascospore wall IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in ascospore wall IDA
Inferred from Direct Assay
more info
 PubMed 
located_in ascus lipid droplet IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm HDA PubMed 
located_in lipid droplet HDA PubMed 
is_active_in lipid droplet IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in lipid droplet IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in prospore membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in prospore membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in prospore membrane IEA
Inferred from Electronic Annotation
more info
  
located_in spore wall IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Lds2p
NP_014595.2
  • Protein Involved in spore wall assembly; localizes to lipid droplets found on or outside of the prospore membrane; shares similarity with Lds1p and Rrt8p, and a strain mutant for all 3 genes exhibits reduced dityrosine fluorescence relative to the single mutants; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    241614..242747 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183301.1 → NP_014595.2  TPA: Lds2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014595.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W220, Q08218
    UniProtKB/TrEMBL
    B3LJ12, C7GK15, C8ZHR7, N1NY32
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q08218.2

Gene LinkOut

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