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BUD21 Bud21p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854245, updated on 28-Oct-2024

Summary

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Official Symbol
BUD21
Official Full Name
Bud21p
Primary source
SGD:S000005604
Locus tag
YOR078W
See related
AllianceGenome:SGD:S000005604; FungiDB:YOR078W; VEuPathDB:YOR078W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
UTP16; YOR29-29
Summary
Enables U3 snoRNA binding activity. Involved in endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Located in nucleolus. Part of small-subunit processome. [provided by Alliance of Genome Resources, Oct 2024]
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Genomic context

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See BUD21 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (472725..473369)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Ski7p Neighboring gene Rts2p Neighboring gene Mn(2+) transporter ATX2 Neighboring gene DNA-binding SCF ubiquitin ligase subunit DIA2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Chemical and Synthetic Genetic Array Analysis Identifies Genes that Suppress Xylose Utilization and Fermentation in Saccharomyces cerevisiae. Usher J, et al. G3 (Bethesda), 2011 Sep. PMID 22384336, Free PMC Article
  2. Deletion of a subgroup of ribosome-related genes minimizes hypoxia-induced changes and confers hypoxia tolerance. Shah AN, et al. Physiol Genomics, 2011 Jul 27. PMID 21586670, Free PMC Article
  3. The size of the nucleus increases as yeast cells grow. Jorgensen P, et al. Mol Biol Cell, 2007 Sep. PMID 17596521, Free PMC Article
  4. The small subunit processome is required for cell cycle progression at G1. Bernstein KA, et al. Mol Biol Cell, 2004 Nov. PMID 15356263, Free PMC Article
  5. RNA polymerase I transcription and pre-rRNA processing are linked by specific SSU processome components. Gallagher JE, et al. Genes Dev, 2004 Oct 15. PMID 15489292, Free PMC Article

See all (83) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables U3 snoRNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables snoRNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of 90S preribosome HDA PubMed 
located_in nucleolus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
part_of small-subunit processome IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Bud21p
NP_014721.1
  • Component of small ribosomal subunit (SSU) processome; interacts with the U3 snoRNA (Snr17a/b); involved in rRNA processing and maturation; required post-transcriptionally for efficient retrotransposition; absence results in decreased Ty1 Gag:GFP protein levels; originally isolated as bud-site selection mutant that displays a random budding pattern; ortholog of human NOL7

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    472725..473369
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183497.1 → NP_014721.1  TPA: Bud21p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014721.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W2E1, O00033, Q08492
    UniProtKB/TrEMBL
    B3LJC7, B5VRX4, C7GT37, C8ZI40, G2WMV6, N1P317
    Conserved Domains (1) summary
    pfam08297
    Location:111 → 208
    U3_snoRNA_assoc; U3 snoRNA associated
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q08492.1

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