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PNS1 Pns1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854332, updated on 2-Nov-2024

Summary

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Official Symbol
PNS1
Official Full Name
Pns1p
Primary source
SGD:S000005687
Locus tag
YOR161C
See related
AllianceGenome:SGD:S000005687; FungiDB:YOR161C; VEuPathDB:YOR161C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Located in plasma membrane. Orthologous to human SLC44A5 (solute carrier family 44 member 5). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See PNS1 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (636939..638558, complement)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene mRNA splicing protein SME1 Neighboring gene Mtr10p Neighboring gene uncharacterized protein Neighboring gene Yrr1p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Reexamining the role of choline transporter-like (Ctlp) proteins in choline transport. Zufferey R, et al. Neurochem Res, 2004 Feb. PMID 15002745
  2. Functional analysis of six genes from chromosomes XIV and XV of Saccharomyces cerevisiae reveals YOR145c as an essential gene and YNL059c/ARP5 as a strain-dependent essential gene encoding nuclear proteins. Grava S, et al. Yeast, 2000 Aug. PMID 10923024
  3. The plasma membrane proteome of Saccharomyces cerevisiae and its response to the antifungal calcofluor. Delom F, et al. Proteomics, 2006 May. PMID 16622836
  4. Ubiquitin-Activated Interaction Traps (UBAITs) identify E3 ligase binding partners. O'Connor HF, et al. EMBO Rep, 2015 Dec. PMID 26508657, Free PMC Article
  5. Large-scale identification of yeast integral membrane protein interactions. Miller JP, et al. Proc Natl Acad Sci U S A, 2005 Aug 23. PMID 16093310, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell periphery HDA PubMed 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane HDA PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Pns1p
NP_014804.3
  • hypothetical protein; has similarity to Torpedo californica tCTL1p, which is postulated to be a choline transporter, neither null mutation nor overexpression affects choline transport

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    636939..638558 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183580.3 → NP_014804.3  TPA: Pns1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014804.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W2L8, Q12412, Q6B2U3
    UniProtKB/TrEMBL
    A6ZP05, B3LJJ3, C7GN64, C8ZGR9, N1NX20
    Conserved Domains (1) summary
    pfam04515
    Location:187 → 510
    Choline_transpo; Plasma-membrane choline transporter
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q12412.1

Gene LinkOut

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