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SRL1 Srl1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854421, updated on 18-Sep-2024

Summary

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Official Symbol
SRL1
Official Full Name
Srl1p
Primary source
SGD:S000005773
Locus tag
YOR247W
See related
AllianceGenome:SGD:S000005773; FungiDB:YOR247W; VEuPathDB:YOR247W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in fungal-type cell wall organization and nucleobase-containing compound metabolic process. Located in cellular bud tip and fungal-type cell wall. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See SRL1 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (797676..798308)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene diacylglycerol O-acyltransferase Neighboring gene Env9p Neighboring gene anaphase promoting complex subunit 5 Neighboring gene cleavage polyadenylation factor subunit CLP1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Localization of a subset of yeast mRNAs depends on inheritance of endoplasmic reticulum. Fundakowski J, et al. Traffic, 2012 Dec. PMID 22994588
  2. Sed1p and Srl1p are required to compensate for cell wall instability in Saccharomyces cerevisiae mutants defective in multiple GPI-anchored mannoproteins. Hagen I, et al. Mol Microbiol, 2004 Jun. PMID 15165243
  3. A role for the Saccharomyces cerevisiae regulation of Ace2 and polarized morphogenesis signaling network in cell integrity. Kurischko C, et al. Genetics, 2005 Oct. PMID 15972461, Free PMC Article
  4. The yeast Cbk1 kinase regulates mRNA localization via the mRNA-binding protein Ssd1. Kurischko C, et al. J Cell Biol, 2011 Feb 21. PMID 21339329, Free PMC Article
  5. New Aspects of Invasive Growth Regulation Identified by Functional Profiling of MAPK Pathway Targets in Saccharomyces cerevisiae. Vandermeulen MD, et al. Genetics, 2020 Sep. PMID 32665277, Free PMC Article

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in cell wall organization IEA
Inferred from Electronic Annotation
more info
  
involved_in fungal-type cell wall organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in nucleobase-containing compound metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cell periphery HDA PubMed 
located_in cell surface IEA
Inferred from Electronic Annotation
more info
  
located_in cellular bud tip IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm HDA PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in fungal-type cell wall IDA
Inferred from Direct Assay
more info
 PubMed 
located_in fungal-type vacuole HDA PubMed 

General protein information

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Preferred Names
Srl1p
NP_014890.1
  • Mannoprotein that exhibits a tight association with the cell wall; required for cell wall stability in the absence of GPI-anchored mannoproteins; has a high serine-threonine content; expression is induced in cell wall mutants; SRL1 has a paralog, SVS1, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    797676..798308
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183666.1 → NP_014890.1  TPA: Srl1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014890.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W2U9, Q08673
    UniProtKB/TrEMBL
    A6ZP86, B3LJR6, B5VSC9, C7GWE1, C8ZGZ9, N1NX98
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q08673.1

Gene LinkOut

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