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RPS10A ribosomal 40S subunit protein S10A [ Saccharomyces cerevisiae S288C ]

Gene ID: 854468, updated on 3-Nov-2024

Summary

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Official Symbol
RPS10A
Official Full Name
ribosomal 40S subunit protein S10A
Primary source
SGD:S000005819
Locus tag
YOR293W
See related
AllianceGenome:SGD:S000005819; FungiDB:YOR293W; VEuPathDB:YOR293W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Involved in ribosomal subunit export from nucleus. Predicted to be located in cytoplasm and ribosome. Predicted to be part of cytosolic small ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 9. Orthologous to several human genes including RPS10 (ribosomal protein S10). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See RPS10A in Genome Data Viewer
Location:
chromosome: XV
Exon count:
2
Sequence:
Chromosome: XV; NC_001147.6 (867098..867852)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene putative acid anhydride hydrolase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Rrs1p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Rps26 directs mRNA-specific translation by recognition of Kozak sequence elements. Ferretti MB, et al. Nat Struct Mol Biol, 2017 Sep. PMID 28759050, Free PMC Article
  2. Cost-effective and rapid lysis of Saccharomyces cerevisiae cells for quantitative western blot analysis of proteins, including phosphorylated eIF2α. Lee SJ, et al. Yeast, 2017 Sep. PMID 28568773
  3. Gcn1 contacts the small ribosomal protein Rps10, which is required for full activation of the protein kinase Gcn2. Lee SJ, et al. Biochem J, 2015 Mar 15. PMID 25437641
  4. Genetic Regulation of Dna2 Localization During the DNA Damage Response. Yimit A, et al. G3 (Bethesda), 2015 Jul 10. PMID 26163422, Free PMC Article
  5. Ribosomal protein genes RPS10 and RPS26 are commonly mutated in Diamond-Blackfan anemia. Doherty L, et al. Am J Hum Genet, 2010 Feb 12. PMID 20116044, Free PMC Article

See all (78) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome NAS
Non-traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytoplasmic translation NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in ribosomal subunit export from nucleus IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of cytosolic small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic small ribosomal subunit NAS
Non-traceable Author Statement
more info
 PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ribosomal 40S subunit protein S10A
NP_014936.1
  • Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S10, no bacterial homolog; RPS10A has a paralog, RPS10B, that arose from the whole genome duplication; mutations in the human homolog associated with Diamond-Blackfan anemia

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    867098..867852
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183712.1 → NP_014936.1  TPA: ribosomal 40S subunit protein S10A [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014936.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W2Z1, Q08745
    UniProtKB/TrEMBL
    A6ZPC8, B3LJV7, C7GNW8, C8ZH43, G2WNF9, N1NYV2
    Conserved Domains (1) summary
    COG5045
    Location:1 → 105
    COG5045; Ribosomal protein S10E [Translation, ribosomal structure and biogenesis]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q08745.1

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