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BUD7 exomer complex subunit [ Saccharomyces cerevisiae S288C ]

Gene ID: 854475, updated on 3-Nov-2024

Summary

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Official Symbol
BUD7
Official Full Name
exomer complex subunit
Primary source
SGD:S000005825
Locus tag
YOR299W
See related
AllianceGenome:SGD:S000005825; FungiDB:YOR299W; VEuPathDB:YOR299W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in Golgi to plasma membrane transport; cellular bud site selection; and chitin biosynthetic process. Located in trans-Golgi network transport vesicle. Part of exomer complex. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See BUD7 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (878435..880675)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Mum3p Neighboring gene multiprotein-bridging factor 1 Neighboring gene Rax1p Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic analysis of the bipolar pattern of bud site selection in the yeast Saccharomyces cerevisiae. Zahner JE, et al. Mol Cell Biol, 1996 Apr. PMID 8657162, Free PMC Article
  2. Exomer: A coat complex for transport of select membrane proteins from the trans-Golgi network to the plasma membrane in yeast. Wang CW, et al. J Cell Biol, 2006 Sep 25. PMID 17000877, Free PMC Article
  3. The complex interactions of Chs5p, the ChAPs, and the cargo Chs3p. Rockenbauch U, et al. Mol Biol Cell, 2012 Nov. PMID 23015758, Free PMC Article
  4. The exomer coat complex transports Fus1p to the plasma membrane via a novel plasma membrane sorting signal in yeast. Barfield RM, et al. Mol Biol Cell, 2009 Dec. PMID 19812245, Free PMC Article
  5. Arf1p, Chs5p and the ChAPs are required for export of specialized cargo from the Golgi. Trautwein M, et al. EMBO J, 2006 Mar 8. PMID 16498409, Free PMC Article

See all (39) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in Golgi to plasma membrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in Golgi to plasma membrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in Golgi to plasma membrane transport IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in cellular bud site selection IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in chitin biosynthetic process IPI
Inferred from Physical Interaction
more info
 PubMed 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
part_of exomer complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of exomer complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of exomer complex IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in trans-Golgi network transport vesicle IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
exomer complex subunit
NP_014943.1
  • Member of the ChAPs family (Chs5p-Arf1p-binding proteins); members include Bch1p, Bch2p, Bud7p, and Chs6p; ChAPs family proteins form the exomer complex with Chs5p to mediate export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane; BUD7 has a paralog, BCH1, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    878435..880675
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183718.1 → NP_014943.1  TPA: exomer complex subunit [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014943.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W2Z9, Q08754
    UniProtKB/TrEMBL
    B3LJW4, C7GNW1, N1NXF5
    Conserved Domains (2) summary
    sd00006
    Location:371 → 400
    TPR; TPR repeat [structural motif]
    pfam09295
    Location:123 → 533
    ChAPs; ChAPs (Chs5p-Arf1p-binding proteins)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q08754.1

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