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SOG2 Sog2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854535, updated on 29-Jun-2024

Summary

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Gene symbol
SOG2
Gene description
Sog2p
Primary source
FungiDB:YOR353C
Locus tag
YOR353C
See related
SGD:S000005880; AllianceGenome:SGD:S000005880; VEuPathDB:YOR353C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable adenylate cyclase activity. Involved in budding cell apical bud growth; septum digestion after cytokinesis; and signal transduction. Located in cellular bud and mating projection tip. Part of incipient cellular bud site. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See SOG2 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (998453..1000828, complement)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene serine/threonine protein kinase MEK1 Neighboring gene TFIIH complex subunit TFB6 Neighboring gene Msc6p Neighboring gene Gds1p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mutations in the C-terminus of the conserved NDR kinase, Cbk1p of Saccharomyces cerevisiae, make the protein independent of upstream activators. Panozzo C, et al. Mol Genet Genomics, 2010 Feb. PMID 19967545
  2. A role for the Saccharomyces cerevisiae regulation of Ace2 and polarized morphogenesis signaling network in cell integrity. Kurischko C, et al. Genetics, 2005 Oct. PMID 15972461, Free PMC Article
  3. RAM: a conserved signaling network that regulates Ace2p transcriptional activity and polarized morphogenesis. Nelson B, et al. Mol Biol Cell, 2003 Sep. PMID 12972564, Free PMC Article
  4. Novel interconnections of HOG signaling revealed by combined use of two proteomic software packages. Janschitz M, et al. Cell Commun Signal, 2019 Jun 17. PMID 31208443, Free PMC Article
  5. Systematic analysis of bypass suppression of essential genes. van Leeuwen J, et al. Mol Syst Biol, 2020 Sep. PMID 32939983, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in budding cell apical bud growth IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cell division IEA
Inferred from Electronic Annotation
more info
  
involved_in septum digestion after cytokinesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in signal transduction IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cellular bud IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in incipient cellular bud site IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mating projection tip IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Sog2p
NP_014998.3
  • Key component of the RAM signaling network; required for proper cell morphogenesis and cell separation after mitosis

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    998453..1000828 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183773.3 → NP_014998.3  TPA: Sog2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014998.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W348, Q08817
    UniProtKB/TrEMBL
    A0A8H4BXE9, G2WNL4, N1NXI7
    Conserved Domains (3) summary
    COG4886
    Location:18 → 266
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00031
    Location:68 → 90
    LRR_1; leucine-rich repeat [structural motif]
    pfam10428
    Location:299 → 781
    SOG2; RAM signalling pathway protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q08817.1

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