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FIT2 Fit2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854564, updated on 2-Nov-2024

Summary

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Official Symbol
FIT2
Official Full Name
Fit2p
Primary source
SGD:S000005909
Locus tag
YOR382W
See related
AllianceGenome:SGD:S000005909; FungiDB:YOR382W; VEuPathDB:YOR382W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in siderophore transport. Located in fungal-type cell wall. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See FIT2 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (1059531..1059992)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene ferric-chelate reductase Neighboring gene uncharacterized protein Neighboring gene Fit3p Neighboring gene putative ferric-chelate reductase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Three cell wall mannoproteins facilitate the uptake of iron in Saccharomyces cerevisiae. Protchenko O, et al. J Biol Chem, 2001 Dec 28. PMID 11673473
  2. The Snf1 protein kinase controls the induction of genes of the iron uptake pathway at the diauxic shift in Saccharomyces cerevisiae. Haurie V, et al. J Biol Chem, 2003 Nov 14. PMID 12960168
  3. Multiple RNA surveillance pathways limit aberrant expression of iron uptake mRNAs and prevent iron toxicity in S. cerevisiae. Lee A, et al. Mol Cell, 2005 Jul 1. PMID 15989963
  4. Loss of vacuolar H+-ATPase (V-ATPase) activity in yeast generates an iron deprivation signal that is moderated by induction of the peroxiredoxin TSA2. Diab HI, et al. J Biol Chem, 2013 Apr 19. PMID 23457300, Free PMC Article
  5. Mitochondrial control of iron homeostasis. A genome wide analysis of gene expression in a yeast frataxin-deficient strain. Foury F, et al. J Biol Chem, 2001 Mar 16. PMID 11112771

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in iron ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in siderophore transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in siderophore transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell periphery HDA PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in fungal-type cell wall IDA
Inferred from Direct Assay
more info
 PubMed 
located_in fungal-type cell wall IEA
Inferred from Electronic Annotation
more info
  
located_in fungal-type vacuole HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in side of membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Fit2p
NP_015027.1
  • Mannoprotein that is incorporated into the cell wall; incorporated via a glycosylphosphatidylinositol (GPI) anchor; involved in the retention of siderophore-iron in the cell wall

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    1059531..1059992
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183802.1 → NP_015027.1  TPA: Fit2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015027.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W375, Q08906
    UniProtKB/TrEMBL
    A6ZPL0, B3LK36, C7GVG4, C8ZHD0, G2WNP2, N1NWA6
    Conserved Domains (1) summary
    pfam17357
    Location:25 → 110
    FIT1_2; Facilitor Of Iron Transport 1 and 2
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q08906.1

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