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Y' element ATP-dependent helicase [ Saccharomyces cerevisiae S288C ]

Gene ID: 854630, updated on 18-Sep-2024

Summary

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Official Full Name
Y' element ATP-dependent helicase
Primary source
SGD:S000001439
Locus tag
YIL177C
See related
AllianceGenome:SGD:S000001439; FungiDB:YIL177C; VEuPathDB:YIL177C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable helicase activity. Predicted to be involved in DNA duplex unwinding. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: IX
Exon count:
2
Sequence:
Chromosome: IX; NC_001141.2 (483..6147, complement)

Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene seripauperin PAU14 Neighboring gene pseudo Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001141.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Y'-Help1, a DNA helicase encoded by the yeast subtelomeric Y' element, is induced in survivors defective for telomerase. Yamada M, et al. J Biol Chem, 1998 Dec 11. PMID 9837911
  2. The heme a synthase Cox15 associates with cytochrome c oxidase assembly intermediates during Cox1 maturation. Bareth B, et al. Mol Cell Biol, 2013 Oct. PMID 23979592, Free PMC Article
  3. Integrating Rio1 activities discloses its nutrient-activated network in Saccharomyces cerevisiae. Iacovella MG, et al. Nucleic Acids Res, 2018 Sep 6. PMID 30011030, Free PMC Article
  4. The nucleotide sequence of Saccharomyces cerevisiae chromosome IX. Churcher C, et al. Nature, 1997 May 29. PMID 9169870
  5. An E3 ubiquitin ligase prevents ectopic localization of the centromeric histone H3 variant via the centromere targeting domain. Ranjitkar P, et al. Mol Cell, 2010 Nov 12. PMID 21070971, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables helicase activity IEA
Inferred from Electronic Annotation
more info
  
enables helicase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in telomere maintenance via recombination IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Y' element ATP-dependent helicase
NP_012092.1
  • Putative Y' element ATP-dependent helicase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001141.2 Reference assembly

    Range
    483..6147 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179522.1 → NP_012092.1  TPA: Y' element ATP-dependent helicase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012092.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VVB6, P40434
    Conserved Domains (5) summary
    COG0513
    Location:607 → 1133
    SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]
    cd00079
    Location:909 → 1013
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam11603
    Location:5 → 88
    Sir1; Regulatory protein Sir1
    cl21455
    Location:676 → 834
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    cl23921
    Location:1556 → 1609
    YccJ; YccJ-like protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P40434.1

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