U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SOA1 Soa1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854640, updated on 28-Oct-2024

Summary

Go to the top of the page Help
Official Symbol
SOA1
Official Full Name
Soa1p
Primary source
SGD:S000001428
Locus tag
YIL166C
See related
AllianceGenome:SGD:S000001428; FungiDB:YIL166C; VEuPathDB:YIL166C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables organic acid transmembrane transporter activity; organic anion transmembrane transporter activity; and sulfate transmembrane transporter activity. Involved in several processes, including inorganic anion transmembrane transport; organic acid transport; and organic anion transport. Located in cell periphery and fungal-type vacuole. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 25; gout; porokeratosis; and sialuria. Orthologous to several human genes including SLC17A1 (solute carrier family 17 member 1); SLC17A2 (solute carrier family 17 member 2); and SLC17A3 (solute carrier family 17 member 3). [provided by Alliance of Genome Resources, Oct 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See SOA1 in Genome Data Viewer
Location:
chromosome: IX
Exon count:
1
Sequence:
Chromosome: IX; NC_001141.2 (30938..32566, complement)

Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene Css1p Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene Nit1p

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_001141.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Phylogenetic classification of the major superfamily of membrane transport facilitators, as deduced from yeast genome sequencing. Nelissen B, et al. FEBS Lett, 1995 Dec 18. PMID 8543057
  2. The Mechanisms of Thiosulfate Toxicity against Saccharomyces cerevisiae. Chen Z, et al. Antioxidants (Basel), 2021 Apr 22. PMID 33922196, Free PMC Article
  3. Major sulfonate transporter Soa1 in Saccharomyces cerevisiae and considerable substrate diversity in its fungal family. Holt S, et al. Nat Commun, 2017 Feb 6. PMID 28165463, Free PMC Article
  4. The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. Boer VM, et al. J Biol Chem, 2003 Jan 31. PMID 12414795
  5. Tup1-Ssn6 and Swi-Snf remodelling activities influence long-range chromatin organization upstream of the yeast SUC2 gene. Fleming AB, et al. Nucleic Acids Res, 2007. PMID 17704134, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables organic acid transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables organic anion transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables sulfate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sulfate transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables sulfur compound transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in modified amino acid transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in nitrogen compound transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in organic acid transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in organic acid transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in organic anion transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in sulfate transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in sulfate transmembrane transport IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in sulfite transmembrane transport IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in sulfur compound transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell periphery HDA PubMed 
located_in fungal-type vacuole HDA PubMed 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Soa1p
NP_012100.1
  • Sulfonate and inorganic sulfur transporter; low affinity sulfate, high affinity sulfite, thiosulfite and major sulfonate transporter; functions as a an H+ symporter; similar to the allantoate permease (Dal5p) subfamily of the major facilitator superfamily; mRNA expression is elevated by sulfur limitation; non-essential gene

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001141.2 Reference assembly

    Range
    30938..32566 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179514.1 → NP_012100.1  TPA: Soa1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012100.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VVC1, P40445
    UniProtKB/TrEMBL
    A0A1D9C0Y0, A6ZVB2, B3LU12, C8ZAU7, G2WFY5, N1P1U7
    Conserved Domains (1) summary
    cd17327
    Location:76 → 496
    MFS_FEN2_like; Pantothenate transporter FEN2 and similar transporters of the Major Facilitator Superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P40445.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools