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ASG1 Asg1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854676, updated on 2-Nov-2024

Summary

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Official Symbol
ASG1
Official Full Name
Asg1p
Primary source
SGD:S000001392
Locus tag
YIL130W
See related
AllianceGenome:SGD:S000001392; FungiDB:YIL130W; VEuPathDB:YIL130W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ASG1 in Genome Data Viewer
Location:
chromosome: IX
Exon count:
1
Sequence:
Chromosome: IX; NC_001141.2 (102782..105676)

Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene Csm2p Neighboring gene forkhead family transcription factor FKH1 Neighboring gene Tao3p Neighboring gene Met18p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001141.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The zinc cluster transcriptional regulator Asg1 transcriptionally coordinates oleate utilization and lipid accumulation in Saccharomyces cerevisiae. Jansuriyakul S, et al. Appl Microbiol Biotechnol, 2016 May. PMID 26875874
  2. A new laboratory evolution approach to select for constitutive acetic acid tolerance in Saccharomyces cerevisiae and identification of causal mutations. González-Ramos D, et al. Biotechnol Biofuels, 2016. PMID 27525042, Free PMC Article
  3. New regulators of drug sensitivity in the family of yeast zinc cluster proteins. Akache B, et al. J Biol Chem, 2002 Jun 14. PMID 11943786
  4. Chromosome-level genome assembly and structural variant analysis of two laboratory yeast strains from the Peterhof Genetic Collection lineage. Barbitoff YA, et al. G3 (Bethesda), 2021 Apr 15. PMID 33677552, Free PMC Article
  5. Life-span extension by pigmented rice bran in the model yeast Saccharomyces cerevisiae. Sunthonkun P, et al. Sci Rep, 2019 Dec 2. PMID 31792269, Free PMC Article

See all (43) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. These results highlight a new role of the transcriptional regulator Asg1 in coordinating expression of genes involved in fatty acid utilization and its role in regulating cellular lipid accumulation.
    Title: The zinc cluster transcriptional regulator Asg1 transcriptionally coordinates oleate utilization and lipid accumulation in Saccharomyces cerevisiae.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding HDA PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in biological_process ND
No biological Data available
more info
  
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Asg1p
NP_012136.1
  • Zinc cluster protein proposed to be a transcriptional regulator; regulator involved in the stress response; regulates utilization of fatty acids and accumulation of lipids

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001141.2 Reference assembly

    Range
    102782..105676
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179478.1 → NP_012136.1  TPA: Asg1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012136.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VVF7, P40467, Q45U13
    UniProtKB/TrEMBL
    B5VKH7
    Conserved Domains (2) summary
    cd12148
    Location:241 → 662
    fungal_TF_MHR; fungal transcription factor regulatory middle homology region
    smart00066
    Location:15 → 56
    GAL4; GAL4-like Zn(II)2Cys6 (or C6 zinc) binuclear cluster DNA-binding domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P40467.1

Gene LinkOut

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