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TIR3 Tir3p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854804, updated on 17-May-2024

Summary

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Gene symbol
TIR3
Gene description
Tir3p
Primary source
FungiDB:YIL011W
Locus tag
YIL011W
See related
SGD:S000001273; AllianceGenome:SGD:S000001273; VEuPathDB:YIL011W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
YIB1
Summary
Predicted to be a structural constituent of cell wall. Predicted to be involved in fungal-type cell wall organization. Located in fungal-type cell wall. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See TIR3 in Genome Data Viewer
Location:
chromosome: IX
Exon count:
1
Sequence:
Chromosome: IX; NC_001141.2 (333727..334536)

Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene ATP-binding cassette multidrug transporter PDR11 Neighboring gene uncharacterized protein Neighboring gene thioredoxin peroxidase DOT5 Neighboring gene telomerase subunit EST3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001141.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Induction of DAN/TIR yeast cell wall mannoprotein genes in response to high hydrostatic pressure and low temperature. Abe F. FEBS Lett, 2007 Oct 16. PMID 17910955
  2. Reciprocal regulation of anaerobic and aerobic cell wall mannoprotein gene expression in Saccharomyces cerevisiae. Abramova N, et al. J Bacteriol, 2001 May. PMID 11292809, Free PMC Article
  3. Impact of Fungal MAPK Pathway Targets on the Cell Wall. Chow J, et al. J Fungi (Basel), 2018 Aug 9. PMID 30096860, Free PMC Article
  4. Identification by comparative transcriptomics of core regulatory genes for higher alcohol production in a top-fermenting yeast at different temperatures in beer fermentation. Sun ZG, et al. Appl Microbiol Biotechnol, 2019 Jun. PMID 31073877
  5. Defining Functions of Mannoproteins in Saccharomyces cerevisiae by High-Dimensional Morphological Phenotyping. Ghanegolmohammadi F, et al. J Fungi (Basel), 2021 Sep 17. PMID 34575807, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables structural constituent of cell wall IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in fungal-type cell wall organization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cell periphery HDA PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
is_active_in fungal-type cell wall IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in fungal-type cell wall IDA
Inferred from Direct Assay
more info
 PubMed 
located_in fungal-type vacuole HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in side of membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Tir3p
NP_012254.1
  • Cell wall mannoprotein; member of Srp1p/Tip1p family of serine-alanine-rich proteins; expressed under anaerobic conditions and required for anaerobic growth; TIR3 has a paralog, TIR2, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001141.2 Reference assembly

    Range
    333727..334536
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179361.1 → NP_012254.1  TPA: Tir3p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012254.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VVR8, P40552
    UniProtKB/TrEMBL
    A0A8H4BZ85, N1P0P0
    Conserved Domains (1) summary
    pfam00660
    Location:20 → 116
    SRP1_TIP1; Seripauperin and TIP1 family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P40552.1

Gene LinkOut

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