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SMA2 Sma2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854936, updated on 2-Nov-2024

Summary

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Official Symbol
SMA2
Official Full Name
Sma2p
Primary source
SGD:S000004531
Locus tag
YML066C
See related
AllianceGenome:SGD:S000004531; FungiDB:YML066C; VEuPathDB:YML066C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in spore membrane bending pathway. Located in cytoplasm and prospore membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See SMA2 in Genome Data Viewer
Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (140424..141533, complement)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene RBR-type E3 ubiquitin transferase Neighboring gene Erv41p Neighboring gene origin recognition complex subunit 1 Neighboring gene Ras family GTPase TEM1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001145.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Dysferlin Domain-Only Protein, Spo73, Is Required for Prospore Membrane Extension in Saccharomyces cerevisiae. Okumura Y, et al. mSphere, 2016 Jan-Feb. PMID 27303688, Free PMC Article
  2. Erv14 family cargo receptors are necessary for ER exit during sporulation in Saccharomyces cerevisiae. Nakanishi H, et al. J Cell Sci, 2007 Mar 1. PMID 17298976
  3. The SpoMBe pathway drives membrane bending necessary for cytokinesis and spore formation in yeast meiosis. Maier P, et al. EMBO J, 2008 Sep 17. PMID 18756268, Free PMC Article
  4. Parallel phenotypic analysis of sporulation and postgermination growth in Saccharomyces cerevisiae. Deutschbauer AM, et al. Proc Natl Acad Sci U S A, 2002 Nov 26. PMID 12432101, Free PMC Article
  5. A screen for genes required for meiosis and spore formation based on whole-genome expression. Rabitsch KP, et al. Curr Biol, 2001 Jul 10. PMID 11470404

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. the SpoMBe pathway of Sma2p and Spo1p involves asymmetric distribution of Sma2p and does not involve a GPI-protein-containing matrix
    Title: The SpoMBe pathway drives membrane bending necessary for cytokinesis and spore formation in yeast meiosis.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in ascospore-type prospore membrane formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in spore membrane bending pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in sporulation resulting in formation of a cellular spore IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in fungal-type vacuole HDA PubMed 
located_in fungal-type vacuole membrane HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in prospore membrane HDA PubMed 
located_in prospore membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in prospore membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Sma2p
NP_013645.1
  • Meiosis-specific prospore membrane protein; required to produce bending force necessary for proper assembly of the prospore membrane during sporulation

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    140424..141533 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182425.1 → NP_013645.1  TPA: Sma2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013645.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A6ZLZ9, D6VZA7, Q04658
    UniProtKB/TrEMBL
    B3LLI9, C8ZED9, G2WJY9, N1P0U6
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q04658.1

Gene LinkOut

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