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uncharacterized protein [ Saccharomyces cerevisiae S288C ]

Gene ID: 854990, updated on 18-Sep-2024

Summary

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Official Full Name
uncharacterized protein
Primary source
SGD:S000004480
Locus tag
YML018C
See related
AllianceGenome:SGD:S000004480; FungiDB:YML018C; VEuPathDB:YML018C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Located in fungal-type vacuole membrane. Orthologous to human SLC35F5 (solute carrier family 35 member F5). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (234771..235952, complement)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene dolichyl-diphosphooligosaccharide--protein glycotransferase Neighboring gene Psp2p Neighboring gene salt homeostasis regulator

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001145.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. YML018C protein localizes to the vacuolar membrane independently of Atg27p. Sturgeon CM, et al. MicroPubl Biol, 2021 May 12. PMID 33997660, Free PMC Article
  2. Regulation of septin dynamics by the Saccharomyces cerevisiae lysine acetyltransferase NuA4. Mitchell L, et al. PLoS One, 2011. PMID 21984913, Free PMC Article
  3. The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII. Bowman S, et al. Nature, 1997 May 29. PMID 9169872
  4. Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Tkach JM, et al. Nat Cell Biol, 2012 Sep. PMID 22842922, Free PMC Article
  5. An in vivo map of the yeast protein interactome. Tarassov K, et al. Science, 2008 Jun 13. PMID 18467557

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in fungal-type vacuole membrane HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in vacuolar membrane IEA
Inferred from Electronic Annotation
more info
  
located_in vacuole IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
NP_013694.1
  • hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the membrane of the vacuole; physical interaction with Atg27p suggests a possible role in autophagy; YML018C is not an essential gene; relative distribution to the vacuolar membrane decreases upon DNA replication stress; YML018C has a paralog, THI74, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    234771..235952 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182376.1 → NP_013694.1  TPA: uncharacterized protein YML018C [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013694.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VZF6, Q03730, Q6B2K7
    UniProtKB/TrEMBL
    A6ZM44, G2WK34, N1NX37
    Conserved Domains (1) summary
    COG0697
    Location:142 → 367
    RhaT; Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q03730.1

Gene LinkOut

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