SPO20 Spo20p [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: SPO20
Official Full Name: Spo20p
Primary source: SGD:S000004619
Locus tag: YMR017W
See related: AllianceGenome:SGD:S000004619; FungiDB:YMR017W; VEuPathDB:YMR017W
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as: DBI9
Summary: Enables SNAP receptor activity; phosphatidic acid binding activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in ascospore-type prospore assembly. Located in nucleus; plasma membrane; and prospore membrane. Part of SNARE complex. Human ortholog(s) of this gene implicated in CEDNIK syndrome. Orthologous to human SNAP29 (synaptosome associated protein 29). [provided by Alliance of Genome Resources, Apr 2022]
NEW: Try the new Gene table
Try the new Transcript table

Chromosome XIII - NC_001145.3 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Interaction of the Spo20 membrane-sensor motif with phosphatidic acid and other anionic lipids is secondary structure-specific.
Title: Interaction of the Spo20 membrane-sensor motif with phosphatidic acid and other anionic lipids, and influence of the membrane environment.
phosphatidic acid stimulates fusion catalyzed by the sporulation-specific t-SNARE light-chain Spo20p
Title: In vitro fusion catalyzed by the sporulation-specific t-SNARE light-chain Spo20p is stimulated by phosphatidic acid.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables SNAP receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables SNAP receptor activity	IPI Inferred from Physical Interaction more info	PubMed
enables SNAP receptor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables phosphatidic acid binding	IDA Inferred from Direct Assay more info	PubMed
enables phosphatidylinositol-4,5-bisphosphate binding	IDA Inferred from Direct Assay more info	PubMed
enables syntaxin binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in ascospore-type prospore assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in exocytosis	IBA Inferred from Biological aspect of Ancestor more info
involved_in membrane fusion	IEA Inferred from Electronic Annotation more info
involved_in sporulation resulting in formation of a cellular spore	IEA Inferred from Electronic Annotation more info
involved_in vesicle fusion	IBA Inferred from Biological aspect of Ancestor more info
involved_in vesicle-mediated transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of SNARE complex	IBA Inferred from Biological aspect of Ancestor more info
part_of SNARE complex	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in prospore membrane	IDA Inferred from Direct Assay more info	PubMed
located_in prospore membrane	IEA Inferred from Electronic Annotation more info
located_in prospore membrane	IMP Inferred from Mutant Phenotype more info	PubMed

NP_013730.1

Meiosis-specific subunit of the t-SNARE complex; required for prospore membrane formation during sporulation; similar to but not functionally redundant with Sec9p; binds to phosphatidic acid; SNAP-25 homolog

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain