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ARA2 D-arabinose 1-dehydrogenase (NAD(P)(+)) ARA2 [ Saccharomyces cerevisiae S288C ]

Gene ID: 855057, updated on 18-Sep-2024

Summary

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Official Symbol
ARA2
Official Full Name
D-arabinose 1-dehydrogenase (NAD(P)(+)) ARA2
Primary source
SGD:S000004644
Locus tag
YMR041C
See related
AllianceGenome:SGD:S000004644; FungiDB:YMR041C; VEuPathDB:YMR041C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables D-arabinose 1-dehydrogenase [NAD(P)+] activity. Involved in dehydro-D-arabinono-1,4-lactone biosynthetic process. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See ARA2 in Genome Data Viewer
Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (350966..351973, complement)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene chromatin-binding transcription coactivator SUB1 Neighboring gene Yet2p Neighboring gene tRNA-Phe Neighboring gene Arg80p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001145.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. NAD+-specific D-arabinose dehydrogenase and its contribution to erythroascorbic acid production in Saccharomyces cerevisiae. Amako K, et al. FEBS Lett, 2006 Nov 27. PMID 17097644
  2. Btn3 regulates the endosomal sorting function of the yeast Ent3 epsin, an adaptor for SNARE proteins. Morvan J, et al. J Cell Sci, 2015 Feb 15. PMID 25512335
  3. Comparative analysis of Saccharomyces cerevisiae WW domains and their interacting proteins. Hesselberth JR, et al. Genome Biol, 2006. PMID 16606443, Free PMC Article
  4. Functional profiling of the Saccharomyces cerevisiae genome. Giaever G, et al. Nature, 2002 Jul 25. PMID 12140549
  5. Functional characterisation of long intergenic non-coding RNAs through genetic interaction profiling in Saccharomyces cerevisiae. Kyriakou D, et al. BMC Biol, 2016 Dec 7. PMID 27927215, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. It demonstrates that Ara2p, not Ara1p, mainly contributes to the production of Erythroascorbic acid from d-arabinose in S. cerevisiae.
    Title: NAD+-specific D-arabinose dehydrogenase and its contribution to erythroascorbic acid production in Saccharomyces cerevisiae.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables D-arabinose 1-dehydrogenase (NAD+) activity IEA
Inferred from Electronic Annotation
more info
  
enables D-arabinose 1-dehydrogenase [NAD(P)+] activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables D-arabinose 1-dehydrogenase [NAD(P)+] activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables D-arabinose 1-dehydrogenase [NAD(P)+] activity IEA
Inferred from Electronic Annotation
more info
  
enables D-arabinose 1-dehydrogenase [NAD(P)+] activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in dehydro-D-arabinono-1,4-lactone biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in dehydro-D-arabinono-1,4-lactone biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
D-arabinose 1-dehydrogenase (NAD(P)(+)) ARA2
NP_013755.1
  • NAD-dependent arabinose dehydrogenase; involved in biosynthesis of dehydro-D-arabinono-1,4-lactone; similar to plant L-galactose dehydrogenase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    350966..351973 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182538.1 → NP_013755.1  TPA: D-arabinose 1-dehydrogenase (NAD(P)(+)) ARA2 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013755.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VZL6, Q04212, Q1XGQ6
    UniProtKB/TrEMBL
    A6ZMA3, B3LLU0, B5VPH1, C7GL78, C8ZEP8, G2WK94, N1NY81
    Conserved Domains (1) summary
    cd19164
    Location:2 → 301
    AKR_ARA2; D-arabinose 1-dehydrogenase (ARA2) and similar proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q04212.1

Gene LinkOut

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