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glucose-6-phosphate 1-epimerase [ Saccharomyces cerevisiae S288C ]

Gene ID: 855125, updated on 2-Nov-2024

Summary

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Official Full Name
glucose-6-phosphate 1-epimerase
Primary source
SGD:S000004705
Locus tag
YMR099C
See related
AllianceGenome:SGD:S000004705; FungiDB:YMR099C; VEuPathDB:YMR099C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables glucose-6-phosphate 1-epimerase activity. Predicted to be involved in carbohydrate metabolic process. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (463934..464827, complement)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene Atp25p Neighboring gene tRNA-Asp Neighboring gene Mub1p Neighboring gene ditrans,polycis-polyprenyl diphosphate synthase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001145.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Glucose-6-phosphate 1-epimerase from bakers' yeast: purification, properties and possible biological function. Wurster B, et al. Hoppe Seylers Z Physiol Chem, 1974 Mar. PMID 4215729
  2. Structure-based functional annotation: yeast ymr099c codes for a D-hexose-6-phosphate mutarotase. Graille M, et al. J Biol Chem, 2006 Oct 6. PMID 16857670
  3. Trz1, the long form RNase Z from yeast, forms a stable heterohexamer with endonuclease Nuc1 and mutarotase. Ma M, et al. Biochem J, 2017 Oct 18. PMID 28899942
  4. Mode of selection and experimental evolution of antifungal drug resistance in Saccharomyces cerevisiae. Anderson JB, et al. Genetics, 2003 Apr. PMID 12702675, Free PMC Article
  5. A consensus of core protein complex compositions for Saccharomyces cerevisiae. Benschop JJ, et al. Mol Cell, 2010 Jun 25. PMID 20620961

See all (45) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
  
enables glucose-6-phosphate 1-epimerase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glucose-6-phosphate 1-epimerase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables glucose-6-phosphate 1-epimerase activity IEA
Inferred from Electronic Annotation
more info
  
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IC
Inferred by Curator
more info
 PubMed 
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus HDA PubMed 

General protein information

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Preferred Names
glucose-6-phosphate 1-epimerase
NP_013817.1
  • Glucose-6-phosphate 1-epimerase (hexose-6-phosphate mutarotase); likely involved in carbohydrate metabolism; GFP-fusion protein localizes to both the nucleus and cytoplasm and is induced in response to the DNA-damaging agent MMS

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    463934..464827 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182599.1 → NP_013817.1  TPA: glucose-6-phosphate 1-epimerase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013817.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VZS2, Q03161
    UniProtKB/TrEMBL
    A6ZMF6, B3LLZ0, B5VPM6, C7GVD6, C8ZEV1, G2WKE7, N1P5I9
    Conserved Domains (1) summary
    COG0676
    Location:1 → 294
    YeaD; D-hexose-6-phosphate mutarotase [Carbohydrate transport and metabolism]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q03161.1

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