U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

YIM1 Yim1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855183, updated on 29-Jun-2024

Summary

Go to the top of the page Help
Gene symbol
YIM1
Gene description
Yim1p
Primary source
FungiDB:YMR152W
Locus tag
YMR152W
See related
SGD:S000004760; AllianceGenome:SGD:S000004760; VEuPathDB:YMR152W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables alcohol dehydrogenase [NAD(P)+] activity. Involved in cellular response to DNA damage stimulus. Located in lipid droplet. Human ortholog(s) of this gene implicated in optic atrophy 10. Orthologous to human RTN4IP1 (reticulon 4 interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See YIM1 in Genome Data Viewer
Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (563096..564193)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene dolichyl-diphosphooligosaccharide-protein glycotransferase Neighboring gene endopeptidase catalytic subunit IMP1 Neighboring gene FG-nucleoporin NUP53 Neighboring gene Rim13p

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_001145.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. YMR152W from Saccharomyces cerevisiae encoding a novel aldehyde reductase for detoxification of aldehydes derived from lignocellulosic biomass. Ouyang Y, et al. J Biosci Bioeng, 2021 Jan. PMID 32967812
  2. Transcriptional response of Saccharomyces cerevisiae to DNA-damaging agents does not identify the genes that protect against these agents. Birrell GW, et al. Proc Natl Acad Sci U S A, 2002 Jun 25. PMID 12077312, Free PMC Article
  3. Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae. Athenstaedt K, et al. J Bacteriol, 1999 Oct. PMID 10515935, Free PMC Article
  4. High confidence proteomic analysis of yeast LDs identifies additional droplet proteins and reveals connections to dolichol synthesis and sterol acetylation. Currie E, et al. J Lipid Res, 2014 Jul. PMID 24868093, Free PMC Article
  5. Growth-Regulated Hsp70 Phosphorylation Regulates Stress Responses and Prion Maintenance. Kao CH, et al. Mol Cell Biol, 2020 May 28. PMID 32205407, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables alcohol dehydrogenase [NAD(P)+] activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA damage response IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in endoplasmic reticulum HDA PubMed 
located_in lipid droplet IDA
Inferred from Direct Assay
more info
 PubMed 
located_in lipid droplet IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Yim1p
NP_013872.1
  • Aldehyde reductase; involved in detoxification of lignocellulose-derived aldehydes; catalyzes the reduction of furan, aliphatic and aromatic aldehydes using either NADH or NADPH as co-factor; membrane of the quinone oxidoreductase subfamily of the medium-chain dehydrogenase/reductase family; null mutant displays sensitivity to DNA damaging agents; protein abundance increases in response to DNA replication stress

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    563096..564193
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182654.1 → NP_013872.1  TPA: Yim1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013872.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A6ZML0, D6VZX3, P28625
    UniProtKB/TrEMBL
    A0A8H4BYV1
    Conserved Domains (1) summary
    cd08247
    Location:8 → 364
    AST1_like; AST1 is a cytoplasmic protein associated with the periplasmic membrane in yeast
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P28625.2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools