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ATR2 Atr2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855322, updated on 29-Jun-2024

Summary

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Gene symbol
ATR2
Gene description
Atr2p
Primary source
FungiDB:YMR279C
Locus tag
YMR279C
See related
SGD:S000004892; AllianceGenome:SGD:S000004892; VEuPathDB:YMR279C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable borate efflux transmembrane transporter activity. Involved in borate transmembrane transport. Located in cell periphery. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See ATR2 in Genome Data Viewer
Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (824729..826351, complement)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene protein serine/threonine phosphatase Neighboring gene phosphoribomutase PRM15 Neighboring gene DNA-binding transcription factor CAT8 Neighboring gene N-acetylglucosaminylphosphatidylinositol deacetylase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001145.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Roles of ATR1 paralogs YMR279c and YOR378w in boron stress tolerance. Bozdag GO, et al. Biochem Biophys Res Commun, 2011 Jun 17. PMID 21621519
  2. Identification of a novel system for boron transport: Atr1 is a main boron exporter in yeast. Kaya A, et al. Mol Cell Biol, 2009 Jul. PMID 19414602, Free PMC Article
  3. Response of genes associated with mitochondrial function to mild heat stress in yeast Saccharomyces cerevisiae. Sakaki K, et al. J Biochem, 2003 Sep. PMID 14561723
  4. Functional characterisation of long intergenic non-coding RNAs through genetic interaction profiling in Saccharomyces cerevisiae. Kyriakou D, et al. BMC Biol, 2016 Dec 7. PMID 27927215, Free PMC Article
  5. The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII. Bowman S, et al. Nature, 1997 May 29. PMID 9169872

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables borate efflux transmembrane transporter activity ISA
Inferred from Sequence Alignment
more info
 PubMed 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in borate transmembrane transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell periphery HDA PubMed 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Atr2p
NP_014006.1
  • Putative boron transporter involved in boron efflux and resistance; overexpression mutant but not null mutant displays boron tolerance phenotype; identified as a heat-induced gene in a high-throughout screen; YMR279C is not an essential gene; YMR279C has a paralog, ATR1, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    824729..826351 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182786.1 → NP_014006.1  TPA: Atr2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014006.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W0A6, Q03263
    UniProtKB/TrEMBL
    A0A6A5PUE5, A6ZMZ5, B3LMG7, B5VQ46, C7GTM0, C8ZFE6, G2WKY8, N1NZ59
    Conserved Domains (1) summary
    cd17476
    Location:74 → 519
    MFS_Amf1_MDR_like; Saccharomyces cerevisiae low affinity ammonium transporter Amf1p/YOR378W, aminotriazole resistance protein Atr1p, and similar transporters of the Major Facilitator Superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q03263.1

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