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AEP2 Aep2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855325, updated on 29-Jun-2024

Summary

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Gene symbol
AEP2
Gene description
Aep2p
Primary source
FungiDB:YMR282C
Locus tag
YMR282C
See related
SGD:S000004895; AllianceGenome:SGD:S000004895; VEuPathDB:YMR282C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
ATP13
Summary
Predicted to enable RNA binding activity. Involved in mitochondrial translational initiation. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See AEP2 in Genome Data Viewer
Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (833356..835098, complement)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcription factor CAT8 Neighboring gene N-acetylglucosaminylphosphatidylinositol deacetylase Neighboring gene tRNA A64-2'-O-ribosylphosphate transferase Neighboring gene tRNA-Tyr

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001145.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Suppression of a nuclear aep2 mutation in Saccharomyces cerevisiae by a base substitution in the 5'-untranslated region of the mitochondrial oli1 gene encoding subunit 9 of ATP synthase. Ellis TP, et al. Genetics, 1999 Apr. PMID 10101162, Free PMC Article
  2. The mature AEP2 gene product of Saccharomyces cerevisiae, required for the expression of subunit 9 of ATP synthase, is a 58 kDa mitochondrial protein. Finnegan PM, et al. FEBS Lett, 1995 Jul 24. PMID 7635208
  3. Incompatibility of nuclear and mitochondrial genomes causes hybrid sterility between two yeast species. Lee HY, et al. Cell, 2008 Dec 12. PMID 19070577
  4. ATP13, a nuclear gene of Saccharomyces cerevisiae essential for the expression of subunit 9 of the mitochondrial ATPase. Ackerman SH, et al. FEBS Lett, 1991 Jan 28. PMID 1825065
  5. Characterization of a yeast nuclear gene, AEP2, required for accumulation of mitochondrial mRNA encoding subunit 9 of the ATP synthase. Finnegan PM, et al. Curr Genet, 1991 Jul. PMID 1718609

See all (46) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in mitochondrial translational initiation IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in regulation of translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrion HDA PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Aep2p
NP_014009.1
  • Mitochondrial protein; likely involved in translation of the mitochondrial OLI1 mRNA; exhibits genetic interaction with the OLI1 mRNA 5'-untranslated leader

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    833356..835098 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182789.1 → NP_014009.1  TPA: Aep2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014009.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B5VQ50, C7GTL7, D6W0A9, P22136, P23115
    UniProtKB/TrEMBL
    A0A8H4F880, N1P609
    Conserved Domains (1) summary
    pfam12921
    Location:317 → 427
    ATP13; Mitochondrial ATPase expression
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P22136.3

Gene LinkOut

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