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AAD14 putative aryl-alcohol dehydrogenase [ Saccharomyces cerevisiae S288C ]

Gene ID: 855385, updated on 2-Nov-2024

Summary

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Official Symbol
AAD14
Official Full Name
putative aryl-alcohol dehydrogenase
Primary source
SGD:S000005275
Locus tag
YNL331C
See related
AllianceGenome:SGD:S000005275; FungiDB:YNL331C; VEuPathDB:YNL331C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables aryl-alcohol dehydrogenase (NADP+) activity. Predicted to be involved in cellular aldehyde metabolic process. Orthologous to human AKR7L (aldo-keto reductase family 7 like (gene/pseudogene)); AKR7A2 (aldo-keto reductase family 7 member A2); and AKR7A3 (aldo-keto reductase family 7 member A3). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See AAD14 in Genome Data Viewer
Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (16118..17248, complement)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene pyridoxine biosynthesis protein SNZ2 Neighboring gene 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase Neighboring gene histone deacetylase RPD3 Neighboring gene AAA family ATPase peroxin 6

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001146.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Deciphering the Origin, Evolution, and Physiological Function of the Subtelomeric Aryl-Alcohol Dehydrogenase Gene Family in the Yeast Saccharomyces cerevisiae. Yang DD, et al. Appl Environ Microbiol, 2018 Jan 1. PMID 29079624, Free PMC Article
  2. Analysis of the seven-member AAD gene set demonstrates that genetic redundancy in yeast may be more apparent than real. Delneri D, et al. Genetics, 1999 Dec. PMID 10581269, Free PMC Article
  3. Disruption of seven hypothetical aryl alcohol dehydrogenase genes from Saccharomyces cerevisiae and construction of a multiple knock-out strain. Delneri D, et al. Yeast, 1999 Nov. PMID 10572264
  4. Functional analysis of eight open reading frames on chromosomes XII and XIV of Saccharomyces cerevisiae. Ahmed Khan S, et al. Yeast, 2000 Dec. PMID 11113969
  5. Stereoselective, biocatalytic reductions of alpha-chloro-beta-keto esters. Kaluzna IA, et al. J Org Chem, 2005 Jan 7. PMID 15624945

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables aryl-alcohol dehydrogenase (NADP+) activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables aryl-alcohol dehydrogenase (NADP+) activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cellular aldehyde metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
putative aryl-alcohol dehydrogenase
NP_014068.1
  • Putative aryl-alcohol dehydrogenase; similar to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role; members of the AAD gene family comprise three pairs (AAD3 + AAD15, AAD6/AAD16 + AAD4, AAD10 + AAD14) whose two genes are more related to one another than to other members of the family

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    16118..17248 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183169.1 → NP_014068.1  TPA: putative aryl-alcohol dehydrogenase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014068.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W0L6, P42884
    UniProtKB/TrEMBL
    A6ZSF1, G2WLE0, N1NWE0
    Conserved Domains (1) summary
    cd19147
    Location:20 → 338
    AKR_AKR9A3_9B1-4; Phanerochaete chrysosporium aryl-alcohol dehydrogenase [NADP(+)] (AAD) and similar proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P42884.1

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